Figure 1 Treponema pallidum Panel b is reproduced with permission from American Society for Microbiology Izard, J. et al. Cryo-electron tomography elucidates the molecular architecture of Treponema pallidum, the syphilis spirochete. J. Bacteriol. 191, 7566–7580 (2009): Journal of Bacteriology, volume 191, 7566–7580, doi: 10.1128/JB.01031- 09. Panel d is reproduced with permission from Liu, J. et al. Cellular architecture of Treponema pallidum: novel flagellum, periplasmic cone, and cell envelope as revealed by cryo electron tomography. J. Mol. Biol. 403, 546–561 (2010), Elsevier. Panel e is reproduced with permission from American Society for Microbiology Izard, J. et al. Cryo-electron tomography elucidates the molecular architecture of Treponema pallidum, the syphilis spirochete. J. Bacteriol. 191, 7566–7580 (2009): Journal of Bacteriology, volume 191, 7566–7580, doi: 10.1128/JB.01031-09 Peeling, R. W. et al. (2017) Syphilis Nat. Rev. Dis. Primers doi:10.1038/nrdp.2017.73