Role of iron, glutathione and lipid peroxidation in ferroptosis.

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Presentation transcript:

Role of iron, glutathione and lipid peroxidation in ferroptosis. Role of iron, glutathione and lipid peroxidation in ferroptosis. Arrows indicate promotion; blunt-ended lines indicate inhibition. GPX4, glutathione peroxidase 4; H2O2, hydrogen peroxide; ·OH , hydroxyl radicals; RSL3, Ras-selective lethal 3; Tf, transferrin; TfR, transferrin receptor. Jieru Wan et al. Stroke Vasc Neurol 2019;svn-2018-000205 © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.