Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest Dominique Shum-Tim, MDa, Mitsugi Nagashima, MDa, Toshiharu.

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Postischemic hyperthermia exacerbates neurologic injury after deep hypothermic circulatory arrest Dominique Shum-Tim, MDa, Mitsugi Nagashima, MDa, Toshiharu Shinoka, MDa, Jan Bucerius, MDa, Georg Nollert, MDa, Hart G. W. Lidov, MDb, Adre du-Plessis, MDc, Peter C. Laussen, MDd, Richard A. Jonas, MDa The Journal of Thoracic and Cardiovascular Surgery Volume 116, Issue 5, Pages 780-792 (November 1998) DOI: 10.1016/S0022-5223(98)00449-8 Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 1 Representative electroencephalographic tracing of seizure in a group III hyperthermic animal. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 2 Mean electroencephalographic amplitude at baseline and at 14 and 48 hours after the operation. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 3 Results of cerebral oxyhemoglobin level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 4 Results of cerebral deoxyhemoglobin level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 5 Results of cytochrome aa3 level by NIRS examination. DPF, Differential path length factor. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 6 NDS on PODs 2, 3, and 4. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 7 OPC on PODs 2, 3, and 4. *P < .05, group I versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions

Fig 8 Histologic scores for neocortex, hippocampus, dentate gyrus, and caudate nucleus. *P < .05, group I versus group III. #P < .05, group II versus group III. The Journal of Thoracic and Cardiovascular Surgery 1998 116, 780-792DOI: (10.1016/S0022-5223(98)00449-8) Copyright © 1998 Mosby, Inc. Terms and Conditions