Effect of anandamide on blood glucose clearance and insulin sensitivity. Effect of anandamide on blood glucose clearance and insulin sensitivity. A: Intraperitoneal.

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Effect of anandamide on blood glucose clearance and insulin sensitivity. Effect of anandamide on blood glucose clearance and insulin sensitivity. A: Intraperitoneal GTT (2 g/kg) and corresponding AUC0–2h calculations. B: Insulin tolerance test (ITT, 0.5 UI/kg). C: Fasting glycemia monitoring. For all experiments, blood samples were collected from the tail tip vein of wild-type mice at the indicated time points, 10 min after an intraperitoneal administration of anandamide (10 mg/kg) or vehicle. Results are expressed as means ± SEM (n = 10). *P < 0.05 vs. corresponding value in vehicle-treated mice. Stephanie Troy-Fioramonti et al. Diabetes 2015;64:808-818 ©2015 by American Diabetes Association