Effect of PP on AT morphology and inflammation after 3 days of treatment. Effect of PP on AT morphology and inflammation after 3 days of treatment. A: Representative figures of adipocytes morphology in epididymal fat of HF-V, HF-PP, and HF-PF. The arrows indicate crown-like structures of macrophages. B: The cross-sectional area of the adipocytes in epididymal fat. C: Relative distribution of adipocyte size in epididymal fat. D: mRNA expression of macrophage markers and proinflammatory cytokines in epididymal fat. E: Mitochondrial mRNA expression in epididymal fat. F: Expression of lipolysis-associated genes in epididymal fat. *P < 0.05. HF-V, n = 8 or 18; HF-PP, n = 8 or 17; HF-PF, n = 8 or 16. (A high-quality digital representation of this figure is available in the online issue.) Dong-Hoon Kim et al. Diabetes 2012;61:2299-2310 ©2012 by American Diabetes Association