Prospective Study of the Incidence, Clinical Features, and Outcome of Symptomatic Upper and Lower Respiratory Tract Infections by Respiratory Viruses.

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Presentation transcript:

Prospective Study of the Incidence, Clinical Features, and Outcome of Symptomatic Upper and Lower Respiratory Tract Infections by Respiratory Viruses in Adult Recipients of Hematopoietic Stem Cell Transplants for Hematologic Malignancies  Rodrigo Martino, Rocío Parody Porras, Nuria Rabella, John V. Williams, Elena Rámila, Nuria Margall, Rosa Labeaga, James E. Crowe, Pedro Coll, Jorge Sierra  Biology of Blood and Marrow Transplantation  Volume 11, Issue 10, Pages 781-796 (October 2005) DOI: 10.1016/j.bbmt.2005.07.007 Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Cumulative incidence of development of a first documented episode of respiratory virus infection in allogeneic transplant recipients. A, Incidence in 86 patients who developed cGVHD according to whether they had (heavy line) or did not have (light line) close household contact with children (<12 years): this incidence was 45% and 19%, respectively, on day +720. B, Incidence in 57 evaluable patients who did not develop cGVHD according to whether they had (heavy line) or did not have (light line) close household contact with children (<12 years): this incidence was 29% and 11%, respectively, on day +720. Biology of Blood and Marrow Transplantation 2005 11, 781-796DOI: (10.1016/j.bbmt.2005.07.007) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Cumulative incidence of development of a first documented episode of respiratory virus infection in autoHSCT recipients. A, Incidence in 92 patients with advanced underlying disease status at transplantation according to whether they had (heavy line) or did not have (light line) close household contact with children (<12 years): this incidence was 18% and 9%, respectively, on day +720. B, Incidence in 148 patients with early underlying disease status at transplantation according to whether they had (heavy line) or did not have (light line) close household contact with children (<12 years): this incidence was 10% and 4%, respectively, on day +720. Biology of Blood and Marrow Transplantation 2005 11, 781-796DOI: (10.1016/j.bbmt.2005.07.007) Copyright © 2005 American Society for Blood and Marrow Transplantation Terms and Conditions