Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated.

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Fig. 5. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated mutations (D1114G or EΔ1279) in its RID co-localizes with wild-type RFP-RPGR1–19 and RFP-RPGRORF15 isoforms and without forming intracellular deposits in COS7 cells. Co-expression analyses of disease mutations in YFP-RPGRIP1α1 with wild-type RFP-RPGR1–19 or RFP-RPGRORF15 in COS7 cells.YFP-RPGRIP1α1 with disease-associated mutations (D1114G or EΔ1279) in its RID co-localizes with wild-type RFP-RPGR1–19 and RFP-RPGRORF15 isoforms and without forming intracellular deposits in COS7 cells. Images shown are representative of cells examined. Scale bar, 25 µm. Hemangi Patil et al. Biology Open 2012;1:140-160 © 2012. Published by The Company of Biologists Ltd