Enrichment of chromatin marks around differentially methylated CpGs.

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Enrichment of chromatin marks around differentially methylated CpGs. Enrichment of chromatin marks around differentially methylated CpGs. We utilized ChIP-seq of short-term cultured human CD34+ cells from the IHEC. Enrichment of histone marks within 250 bp up- and downstream of CpGs with significant DNAm changes upon KD of transcripts 1+3 (A) and transcript 2 (B). The black lines exemplarily depict enrichment around random 50,000 CpGs (background). Enrichment often peaked around the differentially methylated CpGs. Tanja Božić et al. LSA 2018;1:e201800153 © 2018 Božić et al.