Advances in basic and clinical immunology in 2013

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Presentation transcript:

Advances in basic and clinical immunology in 2013 Javier Chinen, MD, PhD, Luigi D. Notarangelo, MD, William T. Shearer, MD, PhD Journal of Allergy and Clinical Immunology Volume 133, Issue 4, Pages 967-976 (April 2014) DOI: 10.1016/j.jaci.2014.01.026 Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Different mechanisms of B-cell tolerance. BAFF-R, B cell–activating factor of the TF family receptor; CSR, class-switch recombination; GC, germinal center; FO, follicular cell; PC, plasma cell. Used with permission from Pieper et al.7 Journal of Allergy and Clinical Immunology 2014 133, 967-976DOI: (10.1016/j.jaci.2014.01.026) Copyright © 2014 American Academy of Allergy, Asthma & Immunology Terms and Conditions