Matthias Nahrendorf et al. JIMG 2009;2:

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Matthias Nahrendorf et al. JIMG 2009;2:1213-1222 PET-CT in ApoE−/− and Statin-Treated Mice PET-CT imaging shows uptake of 18F-4V in the aortic root (arrows) and arch of atherosclerotic mice. Uptake is lower in statin-treated and in wild-type mice. (A, C, E) Short-axis views. (B, D, F) Long-axis views. (G, H, I) Three-dimensional maximum intensity projection. Bone is shown in white, vasculature in blue, and 18F-4V PET signal in red. The PET signal occurs in the carotid arteries, and background signal in the liver, in addition to the strong uptake of 18F-4V PET observed in the root and arch (arrow). K = quantification of PET signal as the standard uptake value (SUV). Mean ± SEM, *p < 0.05. Abbreviations as in Figures 1, 2, and 5. Matthias Nahrendorf et al. JIMG 2009;2:1213-1222 American College of Cardiology Foundation