Fig. 8. Enhancement of the Ptp4E Ptp10D cyst phenotype by elevation of Rho activity.(A) Rho1-CA expression in a wild-type (w1118) background produced strong.

Slides:

Advertisements

Similar presentations

The neuroepithelium of mid-neurulation mammalian embryos displays planar-polarised F-actin profiles. The neuroepithelium of mid-neurulation mammalian embryos.

Advertisements

Scanning electron microscopy analysis of EGK-I to -V chick embryos.

Loss of tight junctions on Rac1 activation in mature cysts.

CK2 is required for early cell divisions in C. elegans embryos

Fig. 6. Ultrastructural changes in the glycocalyx of N

Fig. 1. Overview of the nervous system of the adult S. roscoffensis.

Fig. 7. Vinculin recruitment enhances the efficiency of barrier formation.(A) TER measurements after a calcium switch in α-catenin-depleted MDCK cells.

Fig. 8. In vitro effect of CMPs on adult DSS-treated stomach explants.

Fig. 3. Hts and Dlg are in a complex at the postsynaptic membrane of larval NMJs.(A–B″) PLA with HtsM and Dlg antibodies (green) performed on third instar.

Fig. 1. Representative images of the four cell lines using fluorescence microscopy. Representative images of the four cell lines using fluorescence microscopy.

Targeting of endothelial Rbpj during vessel remodeling.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

Fig. 8. The cohort of 3KO/CCS-LacZ embryos that survived to later timepoints showed marked hyperplasia of the ventricular conduction system (A–F).(B) Severe.

Fig. 10. Ratiometric live imaging of di-4-ANEPPDHQ in growing pollen tubes.(A) Higher and lower membrane order distribution in control and BCD treated.

Fig. 7. Knockdown of Meis1 abolishes CR4. 2-GFP expression

Tbx1 regulates the Mef2c AHF enhancer in vivo.

Remodeling and maturation of the mouse retinal vasculature.

Embryonic corneal defects in E18.5 AP-2β NCC KO mutant embryos.

Fig. 1. Exogenous folic acid and Folr1 rescues the function of a Rho-kinase binding mutation in Shroom3. Exogenous folic acid and Folr1 rescues thefunction.

Fig. 1. Morphological and growth characterization of hBMCs and hPDCs

Scanning EM shows cilia abnormalities in the neural tube.

Fig. 2. Salivary glands from RasV12-expressing larvae produce MMP1, release tissue fragments into the hemolymph and express apoptotic markers.Salivary.

Ectopic sprouting and proliferation in Rbpj veins.

Fig. 1. E-cadherin localizes in nano-scale clusters.

eb1a-2 eb1b-3 double-mutant plants display skewed and shorter roots

Fig. 1. γ-Tubulin localizes in close proximity to centriole walls in interphase but within an extended PCM meshwork in mitosis.U2OS cells were fixed and.

Fig. 2. DDR1 over-expression enhances collagen fibril reorganization

Fig. 8. Knockdown of Meis1 reduces the expression of Foxn4 and Lim1+2

Fig. 3. Characterization of unclassified cells (UCs).

Differentiation of neural crest cells into corneal endothelial cells

Fig. 6. LR phenotype of plastid translation-defective mutants with/without Spec. LR phenotype of plastid translation-defective mutants with/without Spec.

Fig. 4. Non-autonomous rescue of puc expression in DME cells

Epidermal aggregation in clint1 mutants and interaction with lgl2.

Fig. 7. Lhx1-RNAi reduces the eye size

Fig. 3. Rnd proteins induce stronger responses in subconfluent endothelial cells.HUVECs were transfected with Rnd1, Rnd2, Rnd3 or GFP-encoding plasmids.

Fig. 7. Representative images of control (Cas9+GFP) and Cas9+gRNA+GFP co-injected embryos on day 4 of culture, showing nuclear-imported GFP (green) and.

Fig. 6. STK35 KO mice show ovary defects.

Fig. 6. Apical polarity of primitive endoderm cells on surface of embryoid bodies.Embryoid bodies were analyzed by immunofluorescence microscopy for GATA4.

GABAergic subtype switch in the absence of Gata2 in the pTh-R precursors. GABAergic subtype switch in the absence of Gata2 in the pTh-R precursors. (A-T)

Fig. 8. The morphology of the ventral nerve cord in Ror-Myc overexpressing embryos is normal. The morphology of the ventral nerve cord in Ror-Myc overexpressing.

Reb does not play a significant role in regulating TGF-β signaling

Fig. 2. Sufficient rate of recombination in embryonic NSCs and NPCs of Emx1cre knock-in mice.(A) Breeding schemes to generate mice with the Emx1cre locus.

Fig. 1. Phenotypes of RasV12 transformed Drosophila lines

Fig. 1. Polarized F-actin cables in the Xenopus neural plate.

Effect of the plastid translation inhibitor Spec on LR development

Expression analysis of periostin in DRG

Sox2 regulates dental epithelial stem cell proliferation and differentiation. Sox2 regulates dental epithelial stem cell proliferation and differentiation.

Depleting CK2 restores centrosomal ZYG-1 levels in zyg-1(it25) embryos

Fig. 3. Enhanced EGFR signaling in Rhbdf2P159L/P159L mice.

Folic acid increases apical junctional pMLCK localization in vivo

Subcellular localization of prestin and mutant proteins in type I, II and III cells. Subcellular localization of prestin and mutant proteins in type I,

Exo70 is recruited to the plasma membrane at sites of mechanical wounding. Exo70 is recruited to the plasma membrane at sites of mechanical wounding. NRK.

Fig. 3. Overview of an epizoic flatworm capturing a single Artemia nauplius.(A) Flatworm (Waminoa sp.) on the oral disc of its coral host (G. fascicularis),

Fig. 2. Non-homogeneous subcellular distribution of Vangl2 along the anteroposterior axis. Non-homogeneous subcellular distribution of Vangl2 along the.

Prophase nuclear movements in wild-type, rec8 and rec7 mutant cells.

Abnormal adherens junctions between hub cells and GSCs in Lar mutants.

Fig. 4. CR4.2 may be active in amacrine cells but not in ganglion cells.Chick retinas were electroporated with either the control CAG-GFP construct or.

Fig. 1. Expression of the five miRNAs encoded by two miRNA clusters in mouse sperm and oocytes.(A) qPCR analyses of levels of miR-16 (positive control),

Fig. 2. Acetylation stiffens primary cilia.

Fig. 1. Rnd2 and Rnd3 induce stress fibres whereas Rnd1 reduces stress fibres in endothelial cells.(A) Rnd mRNAs are expressed in HUVECs. Total RNA was.

Fig. 3. MO-mediated smc3 knockdown results in reduced regenerate length, segment length and cell proliferation. MO-mediated smc3 knockdown results in reduced.

Fig. 1. Expression of a Ror-eGFP fusion protein under control of the endogenous Ror promoter in Drosophila embryos. Expression of a Ror-eGFP fusion protein.

Fig. 6. Bj mutants show stereocilia patterning defects and biliary duct (BD) malformations. Bj mutants show stereocilia patterning defects and biliary.

Fig. 5. Behaviours of the wild-types Oregon-R at two temperatures.

Fig. 7. Rho family GTPase signaling is required for cyst formation in Ptp4E Ptp10D mutants.(A–C) Expression of DN Rho1 and Rac1 mutants in wild-type (w1118)

Phenotypic analysis of the CNS in mutants for Ror, otk and otk2

Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2.

Novel Functions for Integrins in Epithelial Morphogenesis

Presentation transcript:

Fig. 8. Enhancement of the Ptp4E Ptp10D cyst phenotype by elevation of Rho activity.(A) Rho1-CA expression in a wild-type (w1118) background produced strong tracheal morphogenesis defects, including loss of intersegmental fusion of the DT (arrows) and LT (arrowheads). Enhancement of the Ptp4E Ptp10D cyst phenotype by elevation of Rho activity.(A) Rho1-CA expression in a wild-type (w1118) background produced strong tracheal morphogenesis defects, including loss of intersegmental fusion of the DT (arrows) and LT (arrowheads). (B) Rho1-CA expression in the Ptp4E Ptp10D background converted the TC/LT region into bubble-like structures (arrows). Cysts were present on most DBs (B,C, arrowheads) (see also Fig. 3E). (D,E) Visualization of LT bubble networks at higher magnification, using double-staining with anti-Crumbs (apical marker; green) and anti-E-cadherin (junctional marker; magenta/white). (E) shows that adherens junction markers were present within some of the bubbles. (F–H) When DN RTKs were expressed together with Rho1-CA in Ptp4E Ptp10D embryos, the TC/LT regions still had abnormal morphologies like those in (B). Arrows in (F) and (H) indicate DB cysts in Egfr-DN and Pvr-DN-expressing embryos. Scale bars for (A,B,F–H): 20 µm; for (C–E): 10 µm). Mili Jeon et al. Biology Open 2012;bio.2012471 © 2012. Published by The Company of Biologists Ltd