Longitudinal changes in hyperinflation parameters and exercise capacity after giant bullous emphysema surgery  Rémi Neviere, MD, PhD, Michèle Catto, MD, Nathalie Bautin, MD, Sophie Robin, MD, Henri Porte, MD, PhD, Jacques Desbordes, MD, Régis Matran, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 132, Issue 5, Pages 1203-1207 (November 2006) DOI: 10.1016/j.jtcvs.2006.08.002 Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 1 Resting pulmonary function testing at baseline and after lung resestion surgery in all 12 patients. Forced expiratory volume in 1 second (FEV1), inspiratory capacity (IC), and inspiratory capacity/total lung capacity (IC/TLC) are presented as mean ± SD. *P < .05 compared with controls (values before surgery). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 1203-1207DOI: (10.1016/j.jtcvs.2006.08.002) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 2 Ventilatory response during exercise at exercise isotime before and after surgery in all 12 patients. Tidal volume (VT) and dynamic inspiratory capacity (IC) were significantly increased after surgery (top). Minute ventilation (VE) and breathing frequency (fR) were significantly reduced after surgery (bottom). Results are mean ± SD. *P < .05 compared with controls (values before surgery). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 1203-1207DOI: (10.1016/j.jtcvs.2006.08.002) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions

Figure 3 Cardiovascular and respiratory response during exercise at exercise isotime before and after surgery in all 12 patients. Heart rate (HR) was lower and oxygen (O2) pulse was higher at a given workload after surgery compared with baseline testing (top). Arterial blood gas analysis showed that arterial partial pressure of oxygen Pao2 and alveolar to arterial partial pressure PA-ao2 gradient at a given workload were higher after surgery compared with baseline testing (bottom). Results are mean ± SD; *P < .05 compared with controls (values before surgery). The Journal of Thoracic and Cardiovascular Surgery 2006 132, 1203-1207DOI: (10.1016/j.jtcvs.2006.08.002) Copyright © 2006 The American Association for Thoracic Surgery Terms and Conditions