Thermodynamic analysis of the interaction between diazaborines and M Thermodynamic analysis of the interaction between diazaborines and M. tuberculosis InhA. Thermodynamic analysis of the interaction between diazaborines and M. tuberculosis InhA. Binding of (A) AN12855 and (B, C) AN12908 with M. tuberculosis InhA as measured by ITC. For each compound, the interaction with InhA was measured in either (A, B) the absence of cofactor or (C) the presence of NAD+. InhA, compounds, and cofactors were added as described in the Materials and Methods section. Yi Xia et al. LSA 2018;1:e201800025 © 2018 Xia et al.