Low-dose conjugated equine estrogens elevate circulating neurotransmitters and improve the psychological well-being of menopausal women Arturo Zárate,

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Presentation transcript:

Low-dose conjugated equine estrogens elevate circulating neurotransmitters and improve the psychological well-being of menopausal women Arturo Zárate, M.D., Ph.D., Eugenia Fonseca, B.Sc., Raquel Ochoa, Lourdes Basurto, M.D., Marcelino Hernández, M.D. Fertility and Sterility Volume 77, Issue 5, Pages 952-955 (May 2002) DOI: 10.1016/S0015-0282(02)03077-7

FIGURE 1 Low-dose conjugated equine E (0.312 mg) significantly increased (P <.05) β-endorphin (upper panel). In contrast, noradrenaline (lower panel) decreased (P <.001) after 6 months of treatment. Zárate. HRT improves psychological symptoms and neurotransmitters. Fertil Steril 2002. Fertility and Sterility 2002 77, 952-955DOI: (10.1016/S0015-0282(02)03077-7)

FIGURE 2 Correlations between 17β-E2 and noradrenaline (upper panel) and 17β-E2 and β-endorphin (lower panel) levels were significant (P <.001). Zárate. HRT improves psychological symptoms and neurotransmitters. Fertil Steril 2002. Fertility and Sterility 2002 77, 952-955DOI: (10.1016/S0015-0282(02)03077-7)