The CB1 receptor is one of the most abundant neurotransmitter receptors in the brain
When cannabis is smoked the active principle of this drug, THC, reaches the brain
THC then binds to the CB1 receptor
THC then binds to the CB1 receptor
Cannabis Intoxication THC over-activates the CB1 inducing cannabis intoxication Cannabis Intoxication
Cannabis Intoxication Higher doses of THC, above those found in cannabis smokers, increase pregnenolone levels in the brain THC over-activates the CB1 inducing cannabis intoxication Cannabis Intoxication
Cannabis Intoxication Pregnenolone then binds to a specific site on the CB1 Cannabis Intoxication
Pregnenolone decreases the effects of THC on the CB1
Cannabis intoxication is then reduced Cannabis Effects
Reduced Cannabis Effects Pregnenolone is a natural defense that can protect the brain from cannabis Reduced Cannabis Effects