Aromatase inhibitor treatment of menorrhagia and subsequent pregnancy in a patient with familial hyperparathyroidism–jaw tumor syndrome Erin F. Wolff,

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Presentation transcript:

Aromatase inhibitor treatment of menorrhagia and subsequent pregnancy in a patient with familial hyperparathyroidism–jaw tumor syndrome Erin F. Wolff, M.D., Micah J. Hill, D.O., William F. Simonds, M.D., James H. Segars, M.D. Fertility and Sterility Volume 98, Issue 6, Pages 1616-1619 (December 2012) DOI: 10.1016/j.fertnstert.2012.08.017 Copyright © 2012 Terms and Conditions

Figure 1 Transvaginal ultrasound of the uterus (sagittal view) demonstrating a thickened endometrial lining (red arrow), increased junctional zone, and enlarged cervix (blue arrow) with multiple cystic structures. Fertility and Sterility 2012 98, 1616-1619DOI: (10.1016/j.fertnstert.2012.08.017) Copyright © 2012 Terms and Conditions

Figure 2 Hysteroscopic view of the uterine cavity. Left (A) and right (B) views revealed multiple adenomyomas measuring up to 15 mm in size. Biopsy confirmed adenomyomas. Fertility and Sterility 2012 98, 1616-1619DOI: (10.1016/j.fertnstert.2012.08.017) Copyright © 2012 Terms and Conditions

Figure 3 Surgical specimens were fixed and paraffin embedded. Serial sections were reacted with anti-aromatase antibody. Staining for aromatase in a control endometrial biopsy (A) and an endometrial adenomyoma resected at surgery (B). The latter shows increased staining for aromatase in the mesodermal and glandular hyperparathyroidism–jaw tumor syndrome tissue. Fertility and Sterility 2012 98, 1616-1619DOI: (10.1016/j.fertnstert.2012.08.017) Copyright © 2012 Terms and Conditions