by David Deambrosis, Su Han Lum, Ryan M

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Presentation transcript:

Immune cytopenia post–cord transplant in Hurler syndrome is a forme fruste of graft rejection by David Deambrosis, Su Han Lum, Ryan M. Hum, Kay Poulton, Wendy Ogden, Simon Jones, Simon Stanworth, Denise Bonney, Prashant Hiwarkar, and Robert F. Wynn BloodAdv Volume 3(4):570-574 February 26, 2019 © 2019 by The American Society of Hematology

David Deambrosis et al. Blood Adv 2019;3:570-574 © 2019 by The American Society of Hematology

Risk factors for development of IMC Risk factors for development of IMC. (A) Univariate analysis of risk factors for development of IMC after unrelated cord blood transplant for Hurler syndrome. Risk factors for development of IMC. (A) Univariate analysis of risk factors for development of IMC after unrelated cord blood transplant for Hurler syndrome. Conditioning chemotherapy (FluBu) and preconditioning ALC were significant risk factors for the development of IMC. (B) Box and whisker plot comparing day 0 ALC of patients conditioned with busulfan and cyclophosphamide (BuCy) and FluBu (P = .001). (C) Box and whisker plot comparing preconditioning ALC of patients with and without an episode of IMC (P = .003). GvHD, graft-versus-host disease. David Deambrosis et al. Blood Adv 2019;3:570-574 © 2019 by The American Society of Hematology