Long Live Sox2: Sox2 Lasts a Lifetime

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Presentation transcript:

Long Live Sox2: Sox2 Lasts a Lifetime Grégory Driessens, Cédric Blanpain  Cell Stem Cell  Volume 9, Issue 4, Pages 283-284 (October 2011) DOI: 10.1016/j.stem.2011.09.007 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 Sox2 Expression in Pluripotent Cells, Embryonic Progenitors, and Adult Stem Cells Sox2 is expressed in the inner cell mass of the blastocyst (A) and in the developing embryo. At E15.5, Sox2 is expressed in the foregut endoderm derivatives, as well as in neuronal, inner ear, retina, and lens progenitors (B). In adult mice, Sox2 is expressed in tissue stem cells of stratified and glandular epithelia of ectodermal and endodermal origin, including the glandular stomach, the esophagus, the tongue, the brain, the trachea, and the bronchiolar epithelium, as well as in sensory cells (Merkel and taste bud cells) and spermatogonial stem cells (C). Cell Stem Cell 2011 9, 283-284DOI: (10.1016/j.stem.2011.09.007) Copyright © 2011 Elsevier Inc. Terms and Conditions