The C2H2 zinc-finger factor ztf-16 is required for ver-1 expression.

Slides:

Advertisements

Similar presentations

Schematic drawing of the human X chromosome and physical map the Xp interval carrying the ND gene. A 640-kb yeast artificial chromosome (YAC) clone was.

Advertisements

Studies of protein trap expression We compared the apparent intensity of GFP-protein staining in the GSCs with the RNA level of the corresponding gene.

Membrane topology prediction of the SLC45A2 protein using TMHMM (v. 2

Mark M Metzstein, H.Robert Horvitz Molecular Cell

Leukemic Cellular Retinoic Acid Resistance and Missense Mutations in the PML-RAR Fusion Gene After Relapse of Acute Promyelocytic Leukemia From Treatment.

Ancient Missense Mutations in a New Member of the RoRet Gene Family Are Likely to Cause Familial Mediterranean Fever The International FMF Consortium

Congenital afibrinogenemia: mutations leading to premature termination codons in fibrinogen Aα-chain gene are not associated with the decay of the mutant.

Mutations in the Liver Glycogen Phosphorylase Gene (PYGL) Underlying Glycogenosis Type VI (Hers Disease) Barbara Burwinkel, Henk D. Bakker, Eliezer Herschkovitz,

Jacquelyn Bond, Sheila Scott, Daniel J

Relationship between Genotype and Phenotype

Paola Dal Santo, Mary A Logan, Andrew D Chisholm, Erik M Jorgensen

Deubiquitination of H2B by the SAGA complex destabilizes H2B.

Aoi Nakano, Hajime Nakano, Sal LaForgia, Leena Pulkkinen, Jouni Uitto

Caroline Durrant, Krina T. Zondervan, Lon R

Regulation of Body Size and Behavioral State of C

Model of human CLC-Kb transporter topology and positions of amino acid exchanges due to mutations in the CLCNKB gene as identified in Bartter syndrome.

Volume 10, Issue 4, Pages (April 2006)

Gene structures, positions of mutations, and protein domains of PRP18 paralogs in Arabidopsis. Gene structures, positions of mutations, and protein domains.

Mutations in a Novel Gene with Transmembrane Domains Underlie Usher Syndrome Type 3 Tarja Joensuu, Riikka Hämäläinen, Bo Yuan, Cheryl Johnson, Saara.

A Gene Mutated in Nephronophthisis and Retinitis Pigmentosa Encodes a Novel Protein, Nephroretinin, Conserved in Evolution Edgar Otto, Julia Hoefele,

Volume 91, Issue 6, Pages (December 1997)

Basic SNP characteristics using different filter settings for missing data. Basic SNP characteristics using different filter settings for missing data.

Olfaction and Odor Discrimination Are Mediated by the C

HLA and Pregnancy: The Paradox of the Fetal Allograft

Thomas C. Hart, Yingze Zhang, Michael C. Gorry, P

Phylogenetic tree of perA A2-domain DNA sequence.

lin-35 and lin-53, Two Genes that Antagonize a C

John D. Rioux, Valerie A. Stone, Mark J

Airong Li, Sonia Davila, Laszlo Furu, Qi Qian, Xin Tian, Patrick S

Mutation of Solute Carrier SLC16A12 Associates with a Syndrome Combining Juvenile Cataract with Microcornea and Renal Glucosuria Barbara Kloeckener-Gruissem,

Qiong A. Liu, Michael O. Hengartner Current Biology

Genetic studies into inherited and sporadic hemolytic uremic syndrome

Disrupted in Schizophrenia 1 (DISC1): Association with Schizophrenia, Schizoaffective Disorder, and Bipolar Disorder Colin A. Hodgkinson, David Goldman,

Volume 36, Issue 6, Pages (December 2002)

A Mutation in the Variable Repeat Region of the Aggrecan Gene (AGC1) Causes a Form of Spondyloepiphyseal Dysplasia Associated with Severe, Premature.

M. Bamshad, T. Le, W. S. Watkins, M. E. Dixon, B. E. Kramer, A. D

sac mutants are hypersensitive to IR

Effect of dinB gene deletion on the frequency of spontaneously arisen TetR mutants in different genetic backgrounds. Effect of dinB gene deletion on the.

Identification of AR mutant defects in ABA, ethylene, and auxin response factors. Identification of AR mutant defects in ABA, ethylene, and auxin response.

Heat map of additive effects for PCs QTL

Deletion of PREPL, a Gene Encoding a Putative Serine Oligopeptidase, in Patients with Hypotonia-Cystinuria Syndrome Jaak Jaeken, Kevin Martens, Inge.

Odr-10 Encodes a Seven Transmembrane Domain Olfactory Receptor Required for Responses to the Odorant Diacetyl Piali Sengupta, Joseph H Chou, Cornelia.

Analysis of GFP expression in gfp loss-of-function mutants.

Identification of FOXP2 Truncation as a Novel Cause of Developmental Speech and Language Deficits Kay D. MacDermot, Elena Bonora, Nuala Sykes, Anne-Marie.

Characterization and Mutation Analysis of Human LEFTY A and LEFTY B, Homologues of Murine Genes Implicated in Left-Right Axis Development K. Kosaki,

Volume 12, Issue 17, Pages (September 2002)

Gene ontology (GO) term enrichment for significantly downregulated genes. Gene ontology (GO) term enrichment for significantly downregulated genes. Visualization.

The Gene Mutated in Variant Late-Infantile Neuronal Ceroid Lipofuscinosis (CLN6) and in nclf Mutant Mice Encodes a Novel Predicted Transmembrane Protein

Volume 57, Issue 3, Pages (March 2000)

Molecular Genetics of the Caveolin Gene Family: Implications for Human Cancers, Diabetes, Alzheimer Disease, and Muscular Dystrophy Jeffrey A. Engelman,

The first two principal components for the islet gene expression data for the 181 microarray probes that map to the chromosome 6 trans-eQTL hotspot with.

Fig. 4. transparent encodes Mpv17.(A) tra maps to chromosome 20.

dex-1 mutants form partial dauers.

Sugar Receptors in Drosophila

Mutations in the Gene Encoding Capillary Morphogenesis Protein 2 Cause Juvenile Hyaline Fibromatosis and Infantile Systemic Hyalinosis Sandra Hanks,

(A) yellow cDNA comparison among wild-type and ch mutants

Peter Swoboda, Haskell T. Adler, James H. Thomas Molecular Cell

Exome Sequencing Identifies CCDC8 Mutations in 3-M Syndrome, Suggesting that CCDC8 Contributes in a Pathway with CUL7 and OBSL1 to Control Human Growth

Schematic design of the SSM

Mutational analysis within the 3′ region of the PKD1 gene

Figure 1 Schematic of the OPA3 gene and OPA3 protein isoform b

Whole-chromosome view of gene density, inverse environmental variation, inverse total variation, and open chromatin signature. Whole-chromosome view of.

Extracellular Proteins Needed for C. elegans Mechanosensation

NSD1 Mutations Are the Major Cause of Sotos Syndrome and Occur in Some Cases of Weaver Syndrome but Are Rare in Other Overgrowth Phenotypes Jenny Douglas,

KIT mutations in GISTs. A, amino acid sequence of KIT exon 11 mutations in clinical GIST biopsies. –, amino acids that are deleted; italicized amino acids,

Darryl Y. Nishimura, Ruth E. Swiderski, Charles C. Searby, Erik M

Neurodegenerative Tauopathies

Molecular Characterization of the brd2 Mutation

A, Schematic diagram of identified splice variants of PD-L1.

Volume 18, Issue 6, Pages (June 2010)

Presentation transcript:

The C2H2 zinc-finger factor ztf-16 is required for ver-1 expression. The C2H2 zinc-finger factor ztf-16 is required for ver-1 expression. (A) A schematic of the interval on chromosome X to which mutant allele ns171 was mapped. The flanking SNPs are on cosmids F55D10 (base 14867) and C42D8 (base 5707). The regions spanned by the cosmids used for the rescue experiments shown in B are indicated, as is the position of the ztf-16 gene. (B) The number of lines carrying extrachromosomal arrays of the indicated cosmid that rescued the reduced ver-1 promoter::gfp (nsIs22) expression defect of ns171 mutant adult animals cultivated at 25°. (C) A schematic of the ztf-16 gene: exons are boxed; and regions encoding C2H2 zinc-finger domains are shaded. We isolated two splice forms of ztf-16 on the basis of EST data available from WormBase (release WS225) and have named these gene models ztf-16a and ztf-16b. The mutant ztf-16 alleles isolated in our screen are shown, and the corresponding amino acid change is indicated. Asterisks indicate a premature stop mutation. Carl Procko et al. Genetics 2012;190:1405-1415 Copyright © 2012 by the Genetics Society of America