Expected outcomes Potential problems Research Design Expected outcomes Potential problems
Each Aim Introduction: Promise something interesting Justification and feasibility Review of literature Preliminary data Research design: what will be done Expected outcome: return on investment Potential problems: Timeline Future directions
Sequence for each Aim What will you do? Why does this need to be done? What might go wrong? Should be unlikely Alternative strategies (if hypothesis wrong) What do you expect and why is it important? Future directions: where will this lead?