A suggested model for the role of CPPED1 in glucose metabolism.

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A suggested model for the role of CPPED1 in glucose metabolism. A suggested model for the role of CPPED1 in glucose metabolism. We hypothesize that the improvement in glucose uptake after weight loss could be partly due to the decreased expression of CPPED1, and possibly adiponectin signaling could either directly or indirectly play a role in this regulation. Intact arrows, known effects/effects in cell experiments; dashed arrows, possible interactions; ↑, upregulation; ↓, downregulation. Maija Vaittinen et al. Diabetes 2013;62:3747-3750 ©2013 by American Diabetes Association