Toward the identification of a subset of unexplained infertility: a sperm proteomic approach Susanna McReynolds, Ph.D., Monika Dzieciatkowska, Ph.D., John Stevens, B.S., Kirk C. Hansen, Ph.D., William B. Schoolcraft, M.D., Mandy G. Katz-Jaffe, Ph.D. Fertility and Sterility Volume 102, Issue 3, Pages 692-699 (September 2014) DOI: 10.1016/j.fertnstert.2014.05.021 Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions
Figure 1 Representative Western blot of the sperm protein clusterin (CLU). Western blot analysis of CLU, relative to the housekeeping protein β-tubulin, shows an increased expression in sperm samples that resulted in poor blastocyst development. Group A = sperm resulting in good blastocyst development (>35% grade ≥3 BB). Group B = sperm resulting in poor blastocysts development (<15% grade ≥3 BB). Fertility and Sterility 2014 102, 692-699DOI: (10.1016/j.fertnstert.2014.05.021) Copyright © 2014 American Society for Reproductive Medicine Terms and Conditions