Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteraemia S. Weis, M. Kesselmeier, J.S. Davis,

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Presentation transcript:

Cefazolin versus anti-staphylococcal penicillins for the treatment of patients with Staphylococcus aureus bacteraemia S. Weis, M. Kesselmeier, J.S. Davis, A.M. Morris, S. Lee, A. Scherag, S. Hagel, M.W. Pletz Clinical Microbiology and Infection Volume 25, Issue 7, Pages 818-827 (July 2019) DOI: 10.1016/j.cmi.2019.03.010 Copyright © 2019 The Authors Terms and Conditions

Fig. 1 PRISMA flow diagram of study identification and selection process for outcome analysis 431 (modified from Moher and colleagues) [42]. Clinical Microbiology and Infection 2019 25, 818-827DOI: (10.1016/j.cmi.2019.03.010) Copyright © 2019 The Authors Terms and Conditions

Fig. 2 Results for the primary and the secondary endpoints in patients with Staphylococcus aureus bacteraemia. ASP, anti-staphylococcal penicillins; CI, confidence interval; RR, relative risk. * Data from propensity matched cohort only. Clinical Microbiology and Infection 2019 25, 818-827DOI: (10.1016/j.cmi.2019.03.010) Copyright © 2019 The Authors Terms and Conditions

Fig. 3 Results of the assessment of the impact of a potential inoculum effect in patients with Staphylococcus aureus bacteraemia with endocarditis. ASP, anti-staphylococcal penicillins; CI, confidence interval; RR, relative risk. Clinical Microbiology and Infection 2019 25, 818-827DOI: (10.1016/j.cmi.2019.03.010) Copyright © 2019 The Authors Terms and Conditions

Fig. 4 Results of the assessment of the impact of a potential inoculum effect in patients with Staphylococcus aureus bacteraemia with abscesses. ASP, anti-staphylococcal penicillins; CI, confidence interval; RR, relative risk. Clinical Microbiology and Infection 2019 25, 818-827DOI: (10.1016/j.cmi.2019.03.010) Copyright © 2019 The Authors Terms and Conditions