Transgenic c-Maf mediates upregulation of type 2 cytokines in NOD CD4, but not CD8, cells. Transgenic c-Maf mediates upregulation of type 2 cytokines in.

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Presentation transcript:

Transgenic c-Maf mediates upregulation of type 2 cytokines in NOD CD4, but not CD8, cells. Transgenic c-Maf mediates upregulation of type 2 cytokines in NOD CD4, but not CD8, cells. Cytokine responses of purified lymph node CD4 (top) or CD8 (bottom) cells from NOD/c-Maf ([cjs2110]) or nontransgenic (▪) mice were measured by ELISA using supernatants collected 3 days after anti-CD3 plus anti-CD28 stimulation. Data are plotted as mean ± SD obtained from >3 mice per group assayed in 2-3 independent experiments. *Statistically significant differences between transgenic and nontransgenic values in which P < 0.05 using one-tailed Student's t test. Mary E. Pauza et al. Diabetes 2001;50:39-46 ©2001 by American Diabetes Association

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