Reduced sperm yield from testicular biopsies of vasectomized men is due to increased apoptosis Deirdre A. O’Neill, M.Sc., Carmel M. McVicar, Ph,D., Neil.

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Reduced sperm yield from testicular biopsies of vasectomized men is due to increased apoptosis Deirdre A. O’Neill, M.Sc., Carmel M. McVicar, Ph,D., Neil McClure, F.R.C.O.G., Perry Maxwell, Ph.D., Inez Cooke, M.R.C.O.G., Katherine M. Pogue, B.Sc., Sheena E.M. Lewis, Ph.D. Fertility and Sterility Volume 87, Issue 4, Pages 834-841 (April 2007) DOI: 10.1016/j.fertnstert.2006.11.018 Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 1 Immunopositive apoptotic marker staining in the seminiferous tubule. (A) Fas-positive primary spermatocyte. (B) Bax-positive cytoplasmic staining. (C) Bcl-2-positive leydig cell staining. O’Neill. Sperm yield and apoptosis after vasectomy. Fertil Steril 2007. Fertility and Sterility 2007 87, 834-841DOI: (10.1016/j.fertnstert.2006.11.018) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

FIGURE 2 Correlation between testicular sperm DNA fragmentation and years since vasectomy (r = 0.40, P<.05). O’Neill. Sperm yield and apoptosis after vasectomy. Fertil Steril 2007. Fertility and Sterility 2007 87, 834-841DOI: (10.1016/j.fertnstert.2006.11.018) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions