Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2.

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Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. Lack of Ctip2 is associated with impaired proliferation and delayed onset of differentiation during early stages of epidermal development. (A) Immunofluorescence staining of embryonic skin sections from wild-type (WT) and Ctip2 null (KO) mice with an anti-Ctip2 antibody. (B) Hematoxylin/Eosin-stained sections of dorsal skin collected from WT and KO embryos on the indicated embryonic days. (C–E) Immunofluorescence staining of embryonic skin sections from WT and KO mice with anti-Ki67 (C), anti-K10 (D) and anti-FLG (E) antibodies. The results are representative of at least three independent studies. Abbreviations: D, dermis; E, epidermis. Scale bar: 20 µm. Ling-juan Zhang et al. J Cell Sci 2012;125:5733-5744 © 2012. Published by The Company of Biologists Ltd