Spike timing-dependent plasticity

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Fig. 2 Short-term synaptic plasticity.

Presentation transcript:

Spike timing-dependent plasticity Spike timing-dependent plasticity. a, Synapses are potentiated if the synaptic event precedes the postsynaptic spike. Spike timing-dependent plasticity. a, Synapses are potentiated if the synaptic event precedes the postsynaptic spike. Synapses are depressed if the synaptic event follows the postsynaptic spike. b, The time window for synaptic modification. The relative amount of synaptic change is plotted versus the time difference between synaptic event and the postsynaptic spike. The amount of change falls off exponentially as the time difference increases. In addition, the amount of potentiation decreases for stronger synapses, whereas the relative amount of depression is independent of synaptic size. M. C. W. van Rossum et al. J. Neurosci. 2000;20:8812-8821 ©2000 by Society for Neuroscience