A Kinesin in Command of Primary Ciliogenesis

Slides:

Advertisements

Similar presentations

UpSET Recruits HDAC Complexes and Restricts Chromatin Accessibility and Acetylation at Promoter Regions Hector Rincon-Arano, Jessica Halow, Jeffrey J.

Advertisements

The Bacterial DnaC Helicase Loader Is a DnaB Ring Breaker Ernesto Arias-Palomo, Valerie L. O’Shea, Iris V. Hood, James M. Berger Cell Volume 153, Issue.

Aurora Kinases and Protein Phosphatase 1 Mediate Chromosome Congression through Regulation of CENP-E Yumi Kim, Andrew J. Holland, Weijie Lan, Don W. Cleveland.

Profiling by Image Registration Reveals Common Origin of Annelid Mushroom Bodies and Vertebrate Pallium Raju Tomer, Alexandru S. Denes, Kristin Tessmar-Raible,

SOD1 Integrates Signals from Oxygen and Glucose to Repress Respiration Amit R. Reddi, Valeria C. Culotta Cell Volume 152, Issue 1, Pages (January.

Individualized Medicine from Prewomb to Tomb Eric J. Topol Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell Copyright.

The RAG Recombinase Dictates Functional Heterogeneity and Cellular Fitness in Natural Killer Cells Jenny M. Karo, David G. Schatz, Joseph C. Sun Cell Volume.

The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity Jenni Durieux, Suzanne Wolff, Andrew Dillin Cell Volume 144, Issue 1, Pages.

Bleach Activates a Redox-Regulated Chaperone by Oxidative Protein Unfolding J. Winter, M. Ilbert, P.C.F. Graf, D. Özcelik, U. Jakob Cell Volume 135, Issue.

Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding Aleksandra Helwak, Grzegorz Kudla, Tatiana Dudnakova, David Tollervey.

What We Talk About When We Talk About Fat Evan D. Rosen, Bruce M. Spiegelman Cell Volume 156, Issue 1, Pages (January 2014) DOI: /j.cell

Treatment of Obesity with Celastrol

Maintaining Cell Identity through Global Control of Genomic Organization Gioacchino Natoli Immunity Volume 33, Issue 1, Pages (July 2010) DOI: /j.immuni

Common Sense about Taste: From Mammals to Insects David A. Yarmolinsky, Charles S. Zuker, Nicholas J.P. Ryba Cell Volume 139, Issue 2, Pages (October.

Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm Jianbin Wang, H. Christina Fan, Barry Behr, Stephen.

UvrD Helicase Unwinds DNA One Base Pair at a Time by a Two-Part Power Stroke Jae Young Lee, Wei Yang Cell Volume 127, Issue 7, Pages (December.

Nucleation and Transport Organize Microtubules in Metaphase Spindles Jan Brugués, Valeria Nuzzo, Eric Mazur, Daniel J. Needleman Cell Volume 149, Issue.

Eph-Ephrin Bidirectional Signaling in Physiology and Disease Elena B. Pasquale Cell Volume 133, Issue 1, Pages (April 2008) DOI: /j.cell

Xenobiotics Shape the Physiology and Gene Expression of the Active Human Gut Microbiome Corinne Ferrier Maurice, Henry Joseph Haiser, Peter James Turnbaugh.

Contour Saliency in Primary Visual Cortex Wu Li, Valentin Piëch, Charles D. Gilbert Neuron Volume 50, Issue 6, Pages (June 2006) DOI: /j.neuron

Cancer Metabolism Cell Volume 148, Issue 3, (February 2012) DOI: /j.cell Copyright © 2012 Terms and Conditions Terms and Conditions.

RTEL1 Dismantles T Loops and Counteracts Telomeric G4-DNA to Maintain Telomere Integrity Jean-Baptiste Vannier, Visnja Pavicic-Kaltenbrunner, Mark I.R.

The Monarch Butterfly Genome Yields Insights into Long-Distance Migration Shuai Zhan, Christine Merlin, Jeffrey L. Boore, Steven M. Reppert Cell Volume.

Dynein Anchors Its mRNA Cargo after Apical Transport in the Drosophila Blastoderm Embryo Renald Delanoue, Ilan Davis Cell Volume 122, Issue 1, Pages

Nuclear Receptors, RXR, and the Big Bang Ronald M. Evans, David J. Mangelsdorf Cell Volume 157, Issue 1, Pages (March 2014) DOI: /j.cell

Transmembrane Receptor DCC Associates with Protein Synthesis Machinery and Regulates Translation Joseph Tcherkezian, Perry A. Brittis, Franziska Thomas,

The Landscape of Microsatellite Instability in Colorectal and Endometrial Cancer Genomes Tae-Min Kim, Peter W. Laird, Peter J. Park Cell Volume 155, Issue.

Human Brown Adipose Tissue Sven Enerbäck Cell Metabolism Volume 11, Issue 4, Pages (April 2010) DOI: /j.cmet Copyright © 2010.

The Good Fat Cell Volume 147, Issue 7, (December 2011) DOI: /j.cell Copyright © 2011 Terms and Conditions Terms and Conditions.

Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure Jerome Solon, Aynur Kaya-Çopur, Julien Colombelli,

SRC-3 Coactivator Functional Lifetime Is Regulated by a Phospho-Dependent Ubiquitin Time Clock Ray-Chang Wu, Qin Feng, David M. Lonard, Bert W. O'Malley.

WHAMM Is an Arp2/3 Complex Activator That Binds Microtubules and Functions in ER to Golgi Transport Kenneth G. Campellone, Neil J. Webb, Elizabeth A. Znameroski,

CDK Inhibitors: Cell Cycle Regulators and Beyond Arnaud Besson, Steven F. Dowdy, James M. Roberts Developmental Cell Volume 14, Issue 2, Pages

The Search for Antiaging Interventions: From Elixirs to Fasting Regimens Rafael de Cabo, Didac Carmona-Gutierrez, Michel Bernier, Michael N. Hall, Frank.

Germline Energetics, Aging, and Female Infertility Jonathan L. Tilly, David A. Sinclair Cell Metabolism Volume 17, Issue 6, Pages (June 2013) DOI:

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes Meng-meng Fu, Jeffrey J. Nirschl, Erika L.F.

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles Sandra E. Encalada, Lukasz Szpankowski, Chun-hong Xia,

Mutually Exclusive Binding of Telomerase RNA and DNA by Ku Alters Telomerase Recruitment Model Jennifer S. Pfingsten, Karen J. Goodrich, Cornelius Taabazuing,

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits Yiming Chen, Yen-Chu Lin, Tzu-Wei Kuo, Zachary A. Knight Cell Volume 160, Issue 5,

Volume 1, Issue 1, Pages (June 2007)

Life without Centrioles: Cilia in the Spotlight

Unweaving the Autism Spectrum

Stem Cells Show Parental Control

Elongated Membrane Zones Boost Interactions of Diffusing Proteins

Redefining Clinical Trials: The Age of Personalized Medicine

Volume 154, Issue 1, Pages (July 2013)

Chinmo and Neuroblast Temporal Identity

In This Issue Cell Volume 158, Issue 5, (August 2014)

Organizing Junctions at the Cell-Cell Interface

A Cluster to Remember Cell

Monkey Research in China: Developing a Natural Resource

Spectraplakins: The Cytoskeleton's Swiss Army Knife

Volume 152, Issue 1, (January 2013)

Monkey Research in China: Developing a Natural Resource

TTBK2 Kinase: Linking Primary Cilia and Cerebellar Ataxias

Volume 130, Issue 6, (September 2007)

Easy Stress Relief by EZH2

Volume 143, Issue 6, (December 2010)

Curbing Tregs’ (Lack of) Enthusiasm

Journal of Investigative Dermatology

Making the Most from Changes in Life

The Cell Biology of Genomes: Bringing the Double Helix to Life

Learning from the Uncontrollable

A MAP for Bundling Microtubules

Volume 163, Issue 4, (November 2015)

Volume 163, Issue 2, (October 2015)

Volume 134, Issue 6, (September 2008)

Elongated Membrane Zones Boost Interactions of Diffusing Proteins

In This Issue Cell Volume 145, Issue 3, (April 2011)

Volume 148, Issue 1, (January 2012)

Presentation transcript:

A Kinesin in Command of Primary Ciliogenesis Chad G. Pearson Cell Volume 145, Issue 6, Pages 817-819 (June 2011) DOI: 10.1016/j.cell.2011.05.023 Copyright © 2011 Elsevier Inc. Terms and Conditions

Figure 1 The Transition from Centriole to Basal Body A model for Kif24 regulation of the transition between centriole and basal body functions. Kif24 limits ciliogenesis by recruiting and/or maintaining CP110 at the mother centriole. Coincident with the loss of CP110 from the mother centriole, the centriole becomes a basal body for primary ciliogenesis during the G0 and G1 phases of the cell cycle. Kif24 also binds α/β-tubulin and, through its depolymerase activity, regulates γ-tubulin and posttranslationally modified centriole microtubules to limit ciliogenesis. Cell 2011 145, 817-819DOI: (10.1016/j.cell.2011.05.023) Copyright © 2011 Elsevier Inc. Terms and Conditions