Estrogen and progestogen therapy in postmenopausal women

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Estrogen and progestogen therapy in postmenopausal women Fertility and Sterility Volume 90, Issue 5, Pages S88-S102 (November 2008) DOI: 10.1016/j.fertnstert.2008.08.091 Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 1 Women's Health Initiative hormone trials and coronary heart disease (nonfatal myocardial infarction and death due to CHD). (A, B) Unopposed conjugated equine estrogens (CEE). (C, D) CEE and medroxyprogesterone acetate (MPA). (A, C) Relative hazard for CHD by age. (B, D) Relative hazard for CHD by years since menopause. Bubble point size is proportional to weight (inverse of the variance); horizontal lines are 95% confidence intervals. (Data from Rossouw et al., 2007 [49].) Fertility and Sterility 2008 90, S88-S102DOI: (10.1016/j.fertnstert.2008.08.091) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

Figure 2 Hormone-related indicators of the risk of breast cancer. Data from Singletary 2003 (99) and Clemons and Goss 2001 (100). Fertility and Sterility 2008 90, S88-S102DOI: (10.1016/j.fertnstert.2008.08.091) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions