The effect of benzolamide on NH4+-induced pHi transients in cultured mouse hippocampal neurons. The effect of benzolamide on NH4+-induced pHi transients.

Slides:

Advertisements

Similar presentations

Change in fluorescence / min

Advertisements

Density of dendritic spines on L2/3 pyramidal neurons is greater in visual cortex of germline PirB−/− mice than in PirB+/+ mice at P30. Density of dendritic.

Endogenous phosphorylation of Atp1a3 is regulated by phosphatases.

Hsp27 expression rescues PC12 cells and SCG neurons from JNK-induced cell death and elicits neurite outgrowth. Hsp27 expression rescues PC12 cells and.

Neuronal ATM level is reduced in mouse models of AD

Microglia-synapse interactions in mice following LPS injections.

Calibration of cAMP and forskolin induced FRET ratio and CBF

IQGAPs localize at the tips of axons in hippocampal neurons.

MPP+-induced toxicity in cultured SN and VTA DA neurons.

Parallel Molecular Pathways Mediate Expression of Distinct Forms of Intermediate-Term Facilitation at Tail Sensory–Motor Synapses in Aplysia Michael.

Expression of candidate neuronal IEGs in the brain of cycloheximide pretreated crickets 30 min after PTX injection. Expression of candidate neuronal IEGs.

Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Depolarization-induced postsynaptic NT secretion depends on Ca2+ influx. Hippocampal.

Unaltered presynaptic transmitter secretion during pharmacological treatments. Unaltered presynaptic transmitter secretion during pharmacological treatments.

Neurons in the developing spinal cord express inwardly rectifying K+ channels other than Kir4.1.A, Voltage protocol. Neurons in the developing spinal cord.

Impairments of NMDA receptor-dependent hippocampal synaptic plasticity in DGCs in GirdinSA/SA and Girdin+/− mice. Impairments of NMDA receptor-dependent.

Relationship between hippocampal volume and the number of reported episodic and nonepisodic details. Relationship between hippocampal volume and the number.

Effect of IBMP and PKG on cAMP levels

MSK1 is necessary for BDNF-dependent CREB phosphorylation in area CA1.

HIF-1 is required for IGF-1-induced VEGF mRNA expression and protein secretion. HIF-1 is required for IGF-1-induced VEGF mRNA expression and protein secretion.

Spinal application of naloxone did not change population responses of superficial and deep WDR neurons to graded intracutaneous electrical stimuli in wild-type.

Purkinje cells inhibit large fastigial glycinergic neurons

TeNT did not affect lysosome fusion.

PTZ-induced c-Fos and Arc proteins in hippocampal dentate gyrus

Oligomeric Aβ42 treatment induces expression of Ras and Cyclin D1 and activation of ERK in primary rat cortical neurons. Oligomeric Aβ42 treatment induces.

PTZ-induced neuronal activity visualized by IEGs

Spatiotemporal transmission of tau pathology from additional injection site in non-Tg mice. Spatiotemporal transmission of tau pathology from additional.

Schematic illustration summarizing the effect of orthopedic mice surgery on hippocampal astrocyte-neuron metabolism, structure, and function. Schematic.

Summary data for target shift experiments and transient recall of old memories observed in the second target shift task. Summary data for target shift.

Responses measured by BOLD fMRI in areas V1, V2, V3, and MT+ as two subjects (S2, gray; S3, black) switched between the speed and the contrast discrimination.

PDL-coated beads induce the formation of functional presynaptic terminals within 24 h. PDL-coated beads induce the formation of functional presynaptic.

Quantitative analysis of effects of the Egr inhibitor construct on neurite outgrowth. Quantitative analysis of effects of the Egr inhibitor construct on.

Depolarization-evoked firing activity of hippocampal bipolar neurons that have been dissociated from F344/NSlc and Hiss rats. Depolarization-evoked firing.

Activation of microglial group III mGlu receptors inhibits the release of soluble, stable neurotoxins. Activation of microglial group III mGlu receptors.

CRISPRa induction of Bdnf mRNA increases spike and burst frequency in hippocampal neurons cultured on microelectrode arrays (MEAs). CRISPRa induction of.

Paraquat induces selective loss of subsets of dopaminergic neurons.

Taste cell responses (ΔCa2+) evoked by umami and salty taste stimuli, recorded in a slice preparation of the mouse circumvallate papilla. Taste cell responses.

MET-1 increases DRG neuron K+ currents.

Inhibition of forskolin-induced cAMP accumulation in microglia by group III mGlu receptor agonists and receptor coupling to pertussis toxin-sensitive G-proteins.

Estradiol and diet interact to regulate the number of newborn neurons that express ERα in the ARC and VMH of the adult female mouse. Estradiol and diet.

HFD increased the number of ERα-expressing cells.

Smad1 induces target genes in conditioned DRG neurons.

Gld2 and Ngd regulate glycine-induced GluN2A synthesis and surface expression in dendrites. Gld2 and Ngd regulate glycine-induced GluN2A synthesis and.

SSC LTP in narrow-field vertical neurons is induced by SO stimulation at 20 Hz for 20 s. sSC LTP in narrow-field vertical neurons is induced by SO stimulation.

OGD treatment increased tonic current through an oxidative reaction.

Brain ischemic tolerance model using mouse MCAO

Absence of PC-induced ischemic tolerance in P2X7−/− mice.

Effects of receptor antagonists, Ca2+ channel blocker, Ca2+depletion, and protein kinase inhibitors on CREB phosphorylation in cultured hippocampal neurons.

Rate of current rundown through VDCC and NMDA receptor channels is reduced in gelsolin-deficient hippocampal neurons. Rate of current rundown through VDCC.

Proximal E-box sequence in Bdnf promoter 4 functions as a transcriptional suppressor. Proximal E-box sequence in Bdnf promoter 4 functions as a transcriptional.

Primary structure of zebra finch CREB

Effects of CNO on spontaneous locomotion and amphetamine-induced hyperlocomotion. Effects of CNO on spontaneous locomotion and amphetamine-induced hyperlocomotion.

Target-specific DSI at TRN synapses.

Both the MMP9 and MMP2 systems are activated by anti-Aβ antibodies, IVIg, and mouse IgG. Both the MMP9 and MMP2 systems are activated by anti-Aβ antibodies,

Activation and desensitization of the α7 nAChRs.

MSCaTs measured by GCaMP6f imaging reflect NMDAR activation at individual synapses following spontaneous single vesicle release. mSCaTs measured by GCaMP6f.

FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression. FKBP1b counters the age-related decrease in hippocampal MAP2 protein expression.

SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn exposure. SLC30A10 protects DAergic neurons from neurodegeneration induced by Mn.

A, Representative examples of Ca currents elicited by repetitive 3 Hz depolarizing voltage steps to 0 mV from a holding potential of −40 mV from a CA1.

A, Representative voltage-clamp recordings from a CRF1+ neuron during superfusion of GBZ (100 μm), followed by PTX (100 μm, top trace) and during superfusion.

Leptin-mediated electrophysiological activation of POMC neurons.

ET-1 effect on neuronal viability and blood flow.

Average spontaneous firing rate (SFR) in the different experimental groups grouped according to response category. Average spontaneous firing rate (SFR)

Gene expression in the PFC of mice with an inducible neuron-specific bdnf knock-out in embryogenesis. Gene expression in the PFC of mice with an inducible.

CA1 neuronal loss and recovery following forebrain ischemia.

Dendritic morphology of hippocampal CA1 neurons from wild-type and cbdnf ko animals. Dendritic morphology of hippocampal CA1 neurons from wild-type and.

Effects of rapamycin, cycloheximide, and an MAP kinase inhibitor (U0126) on BDNF-mediated increase in Arc and CaMKII in acute hippocampal slices. Effects.

A, B, 5-HT1A immunoreactivity in hippocampal dendrites (CA3) of saline-treated (A) and fluoxetine-treated (B) rats. A, B, 5-HT1A immunoreactivity in hippocampal.

BDNF protein is expressed in neurons and astrocytes of hippocampus after pilocarpine-induced SE. A, Representative confocal images of hippocampal subfields.

Cluster 4/area 10. a–c, The BOLD coupling patterns of cluster 4 in human subjects (a) and area 10 in macaques (b) and their associated functional connectivity.

Test of visual performance, cortical activity maps and residual S-cone density of the same animal, a ChR2rd1/rd1 mouse, 223 d old. Test of visual performance,

Presentation transcript:

The effect of benzolamide on NH4+-induced pHi transients in cultured mouse hippocampal neurons. The effect of benzolamide on NH4+-induced pHi transients in cultured mouse hippocampal neurons. A, Example of typical sequence of pHi transients elicited by a 5 min exposure to 20 mm NH4+ (for details, see text). B, Amplification of the NH4+-induced alkalinization (NIA) by benzolamide (10 μm in all experiments). The NIA is shown in bold for all figures. Nataliya Svichar et al. J. Neurosci. 2009;29:3252-3258 ©2009 by Society for Neuroscience