Calciphylaxis: Comparison of radiologic imaging and histopathology

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Presentation transcript:

Calciphylaxis: Comparison of radiologic imaging and histopathology Charles L. Halasz, MD, David P. Munger, MD, Heather Frimmer, MD, Michael Dicorato, MD, Sandra Wainwright, MD Journal of the American Academy of Dermatology Volume 77, Issue 2, Pages 241-246.e3 (August 2017) DOI: 10.1016/j.jaad.2017.01.040 Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 1 Calciphylaxis. Patient 1. A, Right buttock ulcer. B, Mediolateral mammographic image of the soft tissues of the left gluteal area. C, Zoomed-in image from the full mammogram. Smallest vessel diameters ranged from 0.2 to 0.3 mm (arrow). Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 2 Calciphylaxis. Patient 2. A, Right calf ulcer. B, Necrosis of tip of penis. C, Mediolateral mammographic image obtained from the right ankle posterior soft tissues. D, Zoomed-in image. Smallest vessel diameters ranged from 0.1 to 0.3 mm (arrow). Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Fig 3 Calciphylaxis. Patient 5. A, Anteroposterior radiograph of the left foot. B, Zoomed-in image from the full radiograph. Smallest vessel diameters ranged from 0.2 to 0.4 mm (arrow). C, Histopathology demonstrated calcification of vessels 0.05 to 0.12 mm. (Original magnification: ×200.) Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Supplementary Fig 1 Calciphylaxis. Patient 3. A, Right leg ulcer. B, Radiographic image of right leg. C, Zoomed-in image shows vessel calcification 0.8 to 1.6 mm in diameter (arrow). Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Supplementary Fig 2 Calciphylaxis. Patient 6. A, Plain film of left foot with vessel calcification 0.2 mm in diameter (arrow). B, Histopathologic image with vessel calcification and thrombosis, and surrounding tissue necrosis. (Original magnification: ×100.) Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions

Supplementary Fig 3 Calciphylaxis. Patient 7. A, Ulcer on right calf. B, Histopathology showing calcification of 0.04-mm vessel. (Original magnification: ×400.) C, Mammographic image of right calf showing calcified vessels, with smallest diameters 0.2 mm (arrows). Journal of the American Academy of Dermatology 2017 77, 241-246.e3DOI: (10.1016/j.jaad.2017.01.040) Copyright © 2017 American Academy of Dermatology, Inc. Terms and Conditions