Atopic endotype in childhood

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Presentation transcript:

Atopic endotype in childhood Ann-Marie Malby Schoos, MD, PhD, Bo Lund Chawes, MD, PhD, Morten Arendt Rasmussen, PhD, Joakim Bloch, MS, Klaus Bønnelykke, MD, PhD, Hans Bisgaard, MD, DMSc Journal of Allergy and Clinical Immunology Volume 137, Issue 3, Pages 844-851.e4 (March 2016) DOI: 10.1016/j.jaci.2015.10.004 Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Prevalence of asthma, eczema, and allergic sensitization during childhood. Journal of Allergy and Clinical Immunology 2016 137, 844-851.e4DOI: (10.1016/j.jaci.2015.10.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 2 Associations between asthma and allergic sensitization to any of the tested allergens, any food allergen, and any inhalant allergen at the 5 age points. Journal of Allergy and Clinical Immunology 2016 137, 844-851.e4DOI: (10.1016/j.jaci.2015.10.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 3 Associations between eczema and allergic sensitization to any of the tested allergens, any food allergen, and any inhalant allergen at the 5 age points. Journal of Allergy and Clinical Immunology 2016 137, 844-851.e4DOI: (10.1016/j.jaci.2015.10.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 4 Temporal phenotype clustering analysis revealing 4 clusters of disease patterns in the cohort (A) and showing how individual children progress through the study (B). Journal of Allergy and Clinical Immunology 2016 137, 844-851.e4DOI: (10.1016/j.jaci.2015.10.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig E1 Venn diagrams showing co-occurrence of eczema (red), allergic sensitization (green), and asthma (blue) at the 5 age points during childhood. Absolute numbers are listed. Journal of Allergy and Clinical Immunology 2016 137, 844-851.e4DOI: (10.1016/j.jaci.2015.10.004) Copyright © 2015 American Academy of Allergy, Asthma & Immunology Terms and Conditions