Marcos D. Guimarães, MD, Marcelo F. K. Benveniste, MD, Almir G. V

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Presentation transcript:

Thymoma Originating in a Giant Thymolipoma: A Rare Intrathoracic Lesion Marcos D. Guimarães, MD, Marcelo F.K. Benveniste, MD, Almir G.V. Bitencourt, MD, Victor P. Andrade, MD, PhD, Liliana P. Souza, MD, Jefferson L. Gross, MD, PhD, Myrna C.B. Godoy, MD, PhD The Annals of Thoracic Surgery Volume 96, Issue 3, Pages 1083-1085 (September 2013) DOI: 10.1016/j.athoracsur.2013.01.031 Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Chest roentgenogram shows almost complete opacification of the right hemithorax, with contralateral displacement of mediastinal structures. The Annals of Thoracic Surgery 2013 96, 1083-1085DOI: (10.1016/j.athoracsur.2013.01.031) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Coronal reformatted computed tomography image with intravenous contrast and mediastinal window setting demonstrates a large heterogeneous mediastinal mass showing areas of soft tissue in the center of the lesion (black *) and areas of fat tissue in the periphery (white *). This lesion has displaced the mediastinal structures to the left and the liver and the right hemidiaphragm inferiorly (arrows). The right lung is almost completely collapsed. The Annals of Thoracic Surgery 2013 96, 1083-1085DOI: (10.1016/j.athoracsur.2013.01.031) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 The macroscopic evaluation of a large intrathoracic lesion that was surgically resected found the lesion was basically composed of adipose tissue (yellowish areas) and thymic tissue (whitish areas), with some hemorrhagic and necrotic areas (thick arrow), and partially recovered by fibrous capsule (thin arrow). The Annals of Thoracic Surgery 2013 96, 1083-1085DOI: (10.1016/j.athoracsur.2013.01.031) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 In the microscopic evaluation with hematoxylin and eosin staining, (A) areas of thymomas subtypes B1 and B2 showed some lymphocytes with mild atypia (thin arrow) and the proliferation of epithelioid cells (thick arrow), and the (B) areas of thymoma subtype B3 showed cells with mitosis and atypical proliferation of epithelioid cells (thin arrow). (Original magnification, (A) ×200; (B) ×400). The Annals of Thoracic Surgery 2013 96, 1083-1085DOI: (10.1016/j.athoracsur.2013.01.031) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions