Language-Selective and Domain-General Regions Lie Side by Side within Broca’s Area  Evelina Fedorenko, John Duncan, Nancy Kanwisher  Current Biology  Volume 22, Issue 21, Pages 2059-2062 (November 2012) DOI: 10.1016/j.cub.2012.09.011 Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 1 Activation Patterns for Five Example Subjects Individual subject activations (red: sentences > nonwords; blue: nonwords > sentences; threshold: p < 0.001, uncorrected; the apparent overlap at the edges of the regions of interest [ROIs] results from the 3D projection of independent regions that overlap along the line of sight). These activations served as the ROIs. Black outlines show BA45/44 borders [11]. Current Biology 2012 22, 2059-2062DOI: (10.1016/j.cub.2012.09.011) Copyright © 2012 Elsevier Ltd Terms and Conditions

Figure 2 Functional Profiles of Language-Selective and Domain-General Functional ROIs Magnitude of response (in percent signal change from the fixation baseline) of language-selective and domain-general regions within BA45 (top box) and BA44 (bottom box) to each of the two conditions in each of the seven tasks. Language-selective regions are defined by intersecting BA45/44 with sentences > nonwords activation, and domain-general regions are defined by intersecting BA45/44 with nonwords > sentences activation. All magnitudes shown are estimated from data independent of those used to define the regions; responses to the sentences and nonwords are estimated using a left-out run. Error bars represent SEM by participants. ∗p < 0.05; ∗∗p < 0.01; ∗∗∗p < 0.001. In the math task, participants added smaller versus larger numbers; in the spatial and verbal working memory (WM) tasks, participants kept in memory fewer versus more locations or digits, respectively; and in the three cognitive control tasks (MSIT, vMSIT, Stroop), participants had to inhibit a prepotent but task-irrelevant response and choose instead the task-relevant response. Current Biology 2012 22, 2059-2062DOI: (10.1016/j.cub.2012.09.011) Copyright © 2012 Elsevier Ltd Terms and Conditions