The protective effect of farm milk consumption on childhood asthma and atopy: The GABRIELA study  Georg Loss, MSc, Silvia Apprich, PhD, Marco Waser, PhD,

Slides:



Advertisements
Similar presentations
Joint modeling of parentally reported and physician-confirmed wheeze identifies children with persistent troublesome wheezing Danielle C.M. Belgrave, MSc,
Advertisements

A bioinformatics approach to identify patients with symptomatic peanut allergy using peptide microarray immunoassay Jing Lin, PhD, Francesca M. Bruni,
Early exposure to cow's milk protein is protective against IgE-mediated cow's milk protein allergy Yitzhak Katz, MD, Nelly Rajuan, MSc, Michael R. Goldberg,
Control of immunopathology during chikungunya virus infection Caroline Petitdemange, PhD, Nadia Wauquier, PhD, Vincent Vieillard, PhD Journal of Allergy.
Characteristics of childhood peanut allergy in the Australian Capital Territory, 1995 to 2007 Raymond James Mullins, MBBS, PhD, FRACP, FRCPA, Keith B.G.
D-dimer: A biomarker for antihistamine-resistant chronic urticaria
What drives prescription patterns in pediatric asthma management?
Association of physical activity, asthma, and allergies: A cohort of farming and nonfarming children  Bettina Bringolf-Isler, MD, PhD, Eva Graf, MD, Marco.
Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children  Markus Johannes.
Ω-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk  Tabea Brick, BA, Yvonne Schober, PhD, Christian Böcking, PhD, Juha.
Santa Jeremy Ono, BA, PhD, Mark B. Abelson, MD 
Prenatal and early-life exposures alter expression of innate immunity genes: The PASTURE cohort study  Georg Loss, MSc, Sondhja Bitter, MD, Johanna Wohlgensinger,
Georg Loss, PhD, Martin Depner, PhD, Laurien H. Ulfman, PhD, R. J
Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood  Anna Lluis, PhD, Martin.
Markus J. Ege, MD, David P. Strachan, MD, William O. C. M
Atopic sensitization in the first year of life
Is 9 more than 2 also in allergic airway inflammation?
Desensitization to Chemotherapeutic Agents
Prediction of the incidence, recurrence, and persistence of atopic dermatitis in adolescence: A prospective cohort study  Astrid S. Peters, MD, MSc, Jessica.
Cord blood cytokines are modulated by maternal farming activities and consumption of farm dairy products during pregnancy: The PASTURE Study  Petra Ina.
An Infant with Atopic Dermatitis and Itching After Ingestion of Milk
Rising prevalence of asthma is sex-specific in a US farming population
Martin Depner, PhD, Markus J. Ege, MD, Michael J
Lieuwe D. Bos, MSc, PhD, Peter J. Sterk, MD, PhD, Stephen J
Antibiotic use in infancy and symptoms of asthma, rhinoconjunctivitis, and eczema in children 6 and 7 years old: International Study of Asthma and Allergies.
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis  George Philip, MD, Janet van Adelsberg, MD, Thomas Loeys, PhD, Nancy.
Physician needs in health informatics: Just ask the docs
Peter M. Wolfgram, MD, David B. Allen, MD 
Etiology of asthma exacerbations
William J. Calhoun, MD, Tmirah Haselkorn, PhD, Dave P
Cats and dogs and the risk of atopy in childhood and adulthood
Jon Genuneit, MD, MSc  Journal of Allergy and Clinical Immunology 
Roles of arginase variants, atopy, and ozone in childhood asthma
Time for a paradigm shift in asthma treatment: From relieving bronchospasm to controlling systemic inflammation  Leif Bjermer, MD  Journal of Allergy.
Is eczema really on the increase worldwide?
Food allergy: A review and update on epidemiology, pathogenesis, diagnosis, prevention, and management  Scott H. Sicherer, MD, Hugh A. Sampson, MD  Journal.
Biosimilars and drug development in allergic and immunologic diseases
Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children  Markus Johannes.
Daphne Koinis-Mitchell, PhD, Timothy Craig, DO, Cynthia A
A cluster-randomized trial shows telephone peer coaching for parents reduces children's asthma morbidity  Jane M. Garbutt, MB, ChB, Yan Yan, MD, PhD,
Medication use in children with asthma in Finland from 1995 to 2006
Autophagy: Nobel Prize 2016 and allergy and asthma research
Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment
Opposite effects of CD14/-260 on serum IgE levels in children raised in different environments  Waltraud Eder, MD, Walt Klimecki, PhD, Lizhi Yu, MD, Erika.
Advances in the approach to the patient with food allergy
Geographic variability in childhood asthma prevalence in Chicago
The role of atopic sensitization in flexural eczema: Findings from the International Study of Asthma and Allergies in Childhood Phase Two  Carsten Flohr,
Prenatal exposure to a farm environment modifies atopic sensitization at birth  Markus Johannes Ege, MD, Ileana Herzum, MD, Gisela Büchele, MPH, Susanne.
Not all farming environments protect against the development of asthma and wheeze in children  Markus Johannes Ege, MD, Remo Frei, MSc, Christian Bieli,
Development of atopic dermatitis according to age of onset and association with early- life exposures  Caroline Roduit, MD, MPH, Remo Frei, PhD, Georg.
Reply Journal of Allergy and Clinical Immunology
Toll-like receptor 2 as a major gene for asthma in children of European farmers  Waltraud Eder, MD, Walt Klimecki, PhD, Lizhi Yu, MD, Erika von Mutius,
Microbial exposure of rural school children, as assessed by levels of N-acetyl-muramic acid in mattress dust, and its association with respiratory health 
Erika von Mutius, MD, MSc  Journal of Allergy and Clinical Immunology 
Protection from childhood asthma and allergy in Alpine farm environments—the GABRIEL Advanced Studies  Sabina Illi, PhD, Martin Depner, PhD, Jon Genuneit,
Association of physical activity, asthma, and allergies: A cohort of farming and nonfarming children  Bettina Bringolf-Isler, MD, PhD, Eva Graf, MD, Marco.
Pınar Uysal, MD, Esben Eller, MSc, PhD, Charlotte G
Measles and immunomodulation
Edith Chen, PhD, Madeleine U. Shalowitz, MD, Rachel E
Increased food diversity in the first year of life is inversely associated with allergic diseases  Caroline Roduit, MD, MPH, Remo Frei, PhD, Martin Depner,
Macrolide antibiotics and asthma treatment
Asthma: The past, future, environment, and costs
The environmental predictors of allergic disease
Placental transfer of allergen-specific IgG but not IgE from a specific immunotherapy– treated mother  Sabine Flicker, PhD, Katharina Marth, MD, Heinz.
Exposure to a farming environment has allergen-specific protective effects on TH2- dependent isotype switching in response to common inhalants  Debra A.
Environmental factors and eosinophilic esophagitis
Farming environments and childhood atopy, wheeze, lung function, and exhaled nitric oxide  Oliver Fuchs, MD, Jon Genuneit, MD, Philipp Latzin, MD, PhD,
Prenatal animal contact and gene expression of innate immunity receptors at birth are associated with atopic dermatitis  Caroline Roduit, MD, MPH, Johanna.
Natural history of cow’s milk allergy
Primary prevention of asthma and allergy
Presentation transcript:

The protective effect of farm milk consumption on childhood asthma and atopy: The GABRIELA study  Georg Loss, MSc, Silvia Apprich, PhD, Marco Waser, PhD, Wolfgang Kneifel, PhD, Jon Genuneit, MD, Gisela Büchele, PhD, Juliane Weber, MD, Barbara Sozanska, MD, Hanna Danielewicz, MD, Elisabeth Horak, MD, R.J. Joost van Neerven, PhD, Dick Heederik, PhD, Peter C. Lorenzen, PhD, Erika von Mutius, MD, Charlotte Braun-Fahrländer, MD  Journal of Allergy and Clinical Immunology  Volume 128, Issue 4, Pages 766-773.e4 (October 2011) DOI: 10.1016/j.jaci.2011.07.048 Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions

Fig 1 Proportion of samples greater than the detection limit in the advanced microbiological analyses (n = 222) shown for each microbiological group stratified by milk type and milk heating status (SM: high heat treated [n = 50], SM: pasteurized [n = 16], FM: heated [n = 55], and FM: raw [n = 101]). FM, Farm milk; SM, shop milk. Journal of Allergy and Clinical Immunology 2011 128, 766-773.e4DOI: (10.1016/j.jaci.2011.07.048) Copyright © 2011 American Academy of Allergy, Asthma & Immunology Terms and Conditions