Iki Adachi, MD, Muhammad S. Khan, MD, Francisco A

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Evolution and Impact of Ventricular Assist Device Program on Children Awaiting Heart Transplantation Iki Adachi, MD, Muhammad S. Khan, MD, Francisco A. Guzmán-Pruneda, MD, Charles D. Fraser, BS, Carlos M. Mery, MD, Susan W. Denfield, MD, William J. Dreyer, MD, David L.S. Morales, MD, E. Dean McKenzie, MD, Jeffrey S. Heinle, MD, Charles D. Fraser, MD The Annals of Thoracic Surgery Volume 99, Issue 2, Pages 635-640 (February 2015) DOI: 10.1016/j.athoracsur.2014.10.010 Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 Graphs showing type of devices used in each era demonstrate dramatic increase in the use of a long-term device (LTVAD) in the late era. The use of a temporary device (either extracorporeal membrane oxygenation or short-term VAD) as a bridge-to-transplantation has largely been abandoned in the late era. Patients with LTVAD are subdivided into those who were bridged from temporary devices to LTVAD and those who directly received LTVAD. The Annals of Thoracic Surgery 2015 99, 635-640DOI: (10.1016/j.athoracsur.2014.10.010) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Competing outcomes on the wait-list for heart transplant (TX) in (A) the early era and in (B) the late era. (MCS = mechanical circulatory support.) The Annals of Thoracic Surgery 2015 99, 635-640DOI: (10.1016/j.athoracsur.2014.10.010) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Kaplan-Meier estimate of survival after bridge-to-transplant. (— = late era, n = 46; - - - = early era, n = 10; p = 0.08.) The Annals of Thoracic Surgery 2015 99, 635-640DOI: (10.1016/j.athoracsur.2014.10.010) Copyright © 2015 The Society of Thoracic Surgeons Terms and Conditions