Insulin sensitivity (Si-clamp) in obese and non-obese study subjects (A) and cumulative incidence of pre-diabetes/type 2 diabetes in insulin-resistant.

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Insulin sensitivity (Si-clamp) in obese and non-obese study subjects (A) and cumulative incidence of pre-diabetes/type 2 diabetes in insulin-resistant obese (IRO), insulin-sensitive obese (ISO), insulin-resistant non-obese (IRN) and insulin-sensitive non-ob... Insulin sensitivity (Si-clamp) in obese and non-obese study subjects (A) and cumulative incidence of pre-diabetes/type 2 diabetes in insulin-resistant obese (IRO), insulin-sensitive obese (ISO), insulin-resistant non-obese (IRN) and insulin-sensitive non-obese (ISN) subjects (B). The cumulative incidence was 48.7% in IRO, 30.9% in ISO, 47.1% in IRN and 26% in ISN groups, respectively (χ2 P for trend=0.0024). (C) Kaplan-Meier plot of pre-diabetes/type 2 diabetes survival among participants stratified by IRO, IRN, ISO or ISN status (log-rank sum p=0.0001). Ibiye Owei et al. BMJ Open Diab Res Care 2017;5:e000415 ©2017 by American Diabetes Association