I-ACQUIRE Webinar for Site PIs and Study Coordinators 22 July 2019 Sharon Ramey and Warren Lo, I-ACQUIRE PIs Stephanie Deluca and Craig Ramey, Directors for the Treatment Implementation Center Jill Heathcock and Amy Darragh, Directors fro the Assessment Center

Update on Key Timeline Activities Training for Local Site Therapists, Study Certification Process, and Plans for Study Monitoring for Each Child. Stephanie DeLuca Training for Local Site Assessors, Study Certification Process, and Plans for Study Monitoring for Each Child. Jill Heathcock Pediatric Neurology: Centralized Review for Clinical MRIs and Baseline Exam for Each Child, including Pediatric Stroke Assessment. Warren Lo Update on Parent Advisory Council. Amy Darragh. Logistics: The MOP; Finalization of all Local Site issues with National Coordinating Center (NCC) in Cincinnati; Training for Use of the MUSC data system known as WebDCU; and Development of Local Site Teams and Plans for “Flow” from Parent Inquiry through Consenting, enrolling, Assessing, treating, and Follow-Up. Scheduling of Local Site “Strategy” Conference Calls

I-ACQUIRE Treatment Protocol Training for Local Site Therapists Study Certification Process Plans for Study Monitoring for Each Child

I-ACQUIRE Assessment Core Training for Local Site Assessors Study Certification Process Plans for Study Monitoring for Each Child Behavioral Measures Parent Surveys

Pediatric Neurology Centralized Review for Clinical MRIs prior to randomization to confirm diagnosis of AIS Baseline Exam for each child Medical history collected by physician Assessment of neurological deficit using the Pediatric Stroke Outcome Measure (0-2yrs version)

Parent Advisory Council Update on Parent Advisory Council

Logistics The MOP Finalization of all Local Site issues with National Coordinating Center (NCC) in Cincinnati Training for Use of the MUSC data system known as WebDCU Development of Local Site Teams and Plans for “Flow”

Scheduling of Local Sites Scheduling of Local Site “Strategy” Conference Calls