Graphical representation of pain levels versus time postinjury, annotated across control, persistently hypersensitive genotypes and diabetic conditions,

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Graphical representation of pain levels versus time postinjury, annotated across control, persistently hypersensitive genotypes and diabetic conditions, and upon constitutive activation of InR. Graphical representation of pain levels versus time postinjury, annotated across control, persistently hypersensitive genotypes and diabetic conditions, and upon constitutive activation of InR. Control, blue solid line; persistently hypersensitive genotypes and diabetic conditions, red dashed line; constitutive activation of InR, green dashed line. Landmark time points (gray vertical bars) and the likely window of ILS activity in nociceptive sensory neurons (orange arrow/text) are indicated. Seol Hee Im et al. Dis. Model. Mech. 2018;11:dmm034231 © 2018. Published by The Company of Biologists Ltd