Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength

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Inflammatory Markers and Loss of Muscle Mass (Sarcopenia) and Strength Laura A. Schaap, MSc, Saskia M.F. Pluijm, PhD, Dorly J.H. Deeg, PhD, Marjolein Visser, PhD The American Journal of Medicine Volume 119, Issue 6, Pages 526.e9-526.e17 (June 2006) DOI: 10.1016/j.amjmed.2005.10.049 Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 1 Study design. The American Journal of Medicine 2006 119, 526.e9-526.e17DOI: (10.1016/j.amjmed.2005.10.049) Copyright © 2006 Elsevier Inc. Terms and Conditions

Figure 2 Odds ratios (with 95% CI) of 3 categories of IL-6 and quartiles of CRP and ACT with loss of muscle strength. Adjusted for age, sex, education level, smoking, number of chronic diseases, alcohol use, physical activity, anti-inflammatory drug use, body mass index, cognitive impairment, and depressive symptoms. *P<.05 versus lowest category; see Methods for cut points categories; 95% CI expressed as vertical line. ACT = α1-antichymotrypsin; CI = confidence interval; CRP = C-reactive protein; IL = interleukin; NHP = normal human pooled plasma. The American Journal of Medicine 2006 119, 526.e9-526.e17DOI: (10.1016/j.amjmed.2005.10.049) Copyright © 2006 Elsevier Inc. Terms and Conditions