Schematic map of the X and Y chromosomes Schematic map of the X and Y chromosomes The X and Y chromosomes are depicted, showing the short (p) and long (q) arms and centromeres (black circle). The pseudoautosomal regions (PAR) 1 and 2 are highlighted in red. The sex-determining genes SRY and DAX1 are indicated. The location of the X inactivation centre (XIC) and the XIST gene is shown. Locations of other genes specifically mentioned in the text are indicated. Maria Jackson et al. Essays Biochem. 2018;62:643-723 ©2018 by Portland Press Ltd