2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia.

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Presentation transcript:

2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. 2DG suppresses of lamellipodia and filopodia and causes disorganization of F-actin filaments in murine endothelial cells. After 24 h of 2DG treatment, SVEC4-10 cells were stained with CellMask, F-actin and DAPI. Formation of lamellipodia (arrows in left column) was impaired and formation of filopodia (middle column) inhibited by 2DG treatment. Scale bars, 10 μm. Chao-Cheng Huang et al. Dis. Model. Mech. 2015;8:1247-1254 © 2015. Published by The Company of Biologists Ltd