Pneumonectomy After Chemoradiation Therapy for Non-Small Cell Lung Cancer: Does “Side” Really Matter?  Anthony W. Kim, MD, L. Penfield Faber, MD, William.

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Presentation transcript:

Pneumonectomy After Chemoradiation Therapy for Non-Small Cell Lung Cancer: Does “Side” Really Matter?  Anthony W. Kim, MD, L. Penfield Faber, MD, William H. Warren, MD, Sanjib Basu, PhD, Sean C. Wightman, BA, James A. Weber, BA, Philip Bonomi, MD, Michael J. Liptay, MD  The Annals of Thoracic Surgery  Volume 88, Issue 3, Pages 937-944 (September 2009) DOI: 10.1016/j.athoracsur.2009.04.102 Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 1 The overall 5-year survival for the entire cohort was 33%. The numbers in the parentheses represent the patients at risk. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 2 Survival stratified according to right-sided (solid line) and left-sided (dashed line) pneumonectomy demonstrated no statistically significant difference at 5 years. The numbers in the parentheses represent the patients at risk. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 3 Survival stratified according to the pathologic stage of complete response (CR, solid line), stage I (small dashed line), stage II (dotted line), stage III (dottted-dashed line), and stage IV (large dashed line). The numbers representing patients at risk were not included for clarity. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 4 Survival stratified according to the pathologic lymph node status of N0 (solid line), N1 (dashed line), and N2 (dotted line). The numbers in the parentheses represent the patients at risk. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 5 The 5-year survival stratified according to nodal downstaging. Node downstage 0 (solid line) was equivalent to no change in pathologic node status from preoperative staging. Node downstage 1 (dashed line) was equivalent to N2 → N1 or N1 → N0 downstaging. Node downstage 2 (dotted line) was equivalent N2 → N0 downstaging. The numbers in the parentheses represent the patients at risk. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

Fig 6 Survival stratified according to the development of complications (dashed line) or no complications (solid line). The numbers in the parentheses represent the patients at risk. The Annals of Thoracic Surgery 2009 88, 937-944DOI: (10.1016/j.athoracsur.2009.04.102) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions