Arrest Duration Influences Postcardioplegia Electrophysiologic Recovery and Reperfusion Arrhythmias  C.Patrick Murrah, Edward R Ferguson, Russell D Spruell,

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Presentation transcript:

Arrest Duration Influences Postcardioplegia Electrophysiologic Recovery and Reperfusion Arrhythmias  C.Patrick Murrah, Edward R Ferguson, Russell D Spruell, William L Holman  The Annals of Thoracic Surgery  Volume 65, Issue 4, Pages 1003-1008 (April 1998) DOI: 10.1016/S0003-4975(98)00079-4

Fig. 1 The most common mechanism for postcardioplegia reperfusion ventricular fibrillation is an accelerating ventricular tachycardia that leads to continuous ventricular electrical activity. (II = limb lead II; aVL = electrocardiographic lead aVL; RAE = right atrial electrogram; RV epi, LV epi = right and left ventricular epicardial electrograms; RV endo, LV endo = right and left ventricular endocardial electrograms.) The Annals of Thoracic Surgery 1998 65, 1003-1008DOI: (10.1016/S0003-4975(98)00079-4)

Fig. 2 In 7 of 167 episodes, postcardioplegia reperfusion ventricular fibrillation occurred without antecedent ventricular tachycardia. (See Fig. 1 for abbreviations.) The Annals of Thoracic Surgery 1998 65, 1003-1008DOI: (10.1016/S0003-4975(98)00079-4)

Fig. 3 The concentration of potassium in coronary sinus blood was measured before, during, and after cardioplegic arrest. (K+ = potassium concentration of coronary sinus blood; sample number: 1 = before bypass; 2 = before cardioplegia infusion on bypass; 3 = 1 minute after initial cardioplegia infusion [all groups]; 4 = 1 minute after cardioplegia at 45 minutes of arrest [groups II and III only]; 5 = 1 minute after cardioplegia at 105 minutes of arrest [group III only]; 6 through 16 = 0.5, 1, 2, 3, 4, 5, 6, 8, 10, 15, and 20 minutes after start of reperfusion.) The Annals of Thoracic Surgery 1998 65, 1003-1008DOI: (10.1016/S0003-4975(98)00079-4)

Fig. 4 The septal myocardial temperature was measured. During reperfusion the myocardial temperature increased rapidly toward normothermia (37°C). There were no statistically significant differences in temperature between groups, although the return of electrophysiologic function differed between groups according to the duration of cardioplegic arrest. (Time = seconds after initiation of postcardioplegia reperfusion.) The Annals of Thoracic Surgery 1998 65, 1003-1008DOI: (10.1016/S0003-4975(98)00079-4)