Structures of P. aeruginosa ExoU and its chaperone, SpcU (PDB ID 3TU3), shown as a cartoon. Structures of P. aeruginosa ExoU and its chaperone, SpcU (PDB.

Slides:



Advertisements
Similar presentations
© red ©
Advertisements

The repeat domain of Tau cross-links to α-tubulin.
Structures of natural cytotoxicity receptors.
DBM‐mimetic binding of KY‐02061 on the Dvl PDZ domain
Frequency of inactivated spores of B
Shielding of bacterial spores against galactic cosmic radiation by meteorite material. Shielding of bacterial spores against galactic cosmic radiation.
Three-dimensional structure of B. subtilis PRPP synthase.
Allosteric site of B. subtilis PRPP synthase.
Diagram of AmpC from E. coli complexed with acylated ceftazidime (PDB accession number 1IEL) (265) created with Cn3CD, version 4.1 (available at
Cross-section of a spore of B. subtilis.
The microsporidian sex-related locus.
Solar spectrum in space (thin line) and on Earth's surface (thick line). Solar spectrum in space (thin line) and on Earth's surface (thick line). Below.
Human ARDS. Photomicrographs from the lungs of 2 different patients with ARDS, stained with hematoxylin and eosin (H&E) are shown. Human ARDS. Photomicrographs.
N-Glycosidic bond formation with PRPP
Phrap assemblies visualized with the Consed (53) program.
Current models of the interactions of proteins within β-carboxysomes.
Catalytic strategies. Catalytic strategies. The coordination of Mg2+ (shown as blue spheres) of the active site to the substrates, to amino acid residues,
Possible secondary structure of the S. enterica prs leader.
Schematic representation of major cell wall components.
The Unfolding Story of a Redox Chaperone
Catalytic mechanism of PRPP synthase.
RLR domains and signaling.
CTL killing and hepatocyte replacement.
AMPK and SNF1: Snuffing Out Stress
Current model for Fe-S cluster assembly by the Suf system.
Structures of hydrophobic signaling molecules produced by diatoms and bacteria. Structures of hydrophobic signaling molecules produced by diatoms and bacteria.
Representative protein structures for bacterial PPIases.
Alignment of N-terminal sequences of type IV pilin proteins.
Summary of major events in Earth history relating to the appearance of eukaryotic groups and the appearance of O2 in the atmosphere and in marine environments.
Drug transport mechanism of AcrB.
PLase cleavage sites in phosphatidylcholine and cellular activities of the reaction products. PLase cleavage sites in phosphatidylcholine and cellular.
Roles of different bacterial SMases and PLases in virulence.
Schematic representation of the hydrolysis of amorphous and microcrystalline cellulose by noncomplexed (A) and complexed (B) cellulase systems. Schematic.
Antibiofilm strategies arising from fundamental research.
Hector H. García et al. Clin. Microbiol. Rev. 2002; doi: /CMR
UV resistance of spores and vegetative cells of B
Scheme for recovery of viral nucleic acid from microarray spots.
T4P gene clusters in C. perfringens and C. difficile.
Protein structures of various PFT classes.
Molecular model of C. pseudotuberculosis Smase D
SMase cleavage sites in sphingomyelin and cellular activities of the reaction products. SMase cleavage sites in sphingomyelin and cellular activities of.
Physiological effects of heat shock.
Simplified neighbor-joining tree of ABC domains.
Prophage genome map of the C. diphtheriae prophage encoding DT
Roberta B. Carey et al. Clin. Microbiol. Rev. 2018; doi: /CMR
Undecaprenyl-linked O antigen polysaccharide precursors (O-PS), initiated by a WecA homologue and elongated at the nonreducing end (black dots), are polymerized.
Molecular models for module exchange between phages.
MEED exposure facility mounted on the camera beam of the lunar orbiter of the Apollo 16 mission (A) and sample cuvette for exposing dry layers of microorganisms.
Structures of four importers.
Structure of an exporter.
Binding of mRNA to the 30S ribosomal subunit.
Modeling of EGFR exon 20 insertions using the 3-dimensional structure of the EGFR kinase domain predicts different interactions with the erlotinib-binding.
Concerted model for maltose transport.
General scheme of the events triggered by C
Conserved motifs in the ABC
Absorption spectra of PRs in relation to light attenuation patterns in different marine environments. Absorption spectra of PRs in relation to light attenuation.
Thermodynamic cycle for ligand binding to a periplasmic-BP.
General overview of the bioinformatic pipelines for the 16S rRNA gene microbial profiling and shotgun metagenomics. General overview of the bioinformatic.
Alignment of PilT retraction ATPases.
Repair kinetics of radiation-induced DNA damage under microgravity conditions. Repair kinetics of radiation-induced DNA damage under microgravity conditions.
Splice isoforms of the JNK1, JNK2, and JNK3 proteins.
IF2 and structural homologues.
Diagrammatic representation of individual cnidarian host gastrodermal cells with resident symbionts. Diagrammatic representation of individual cnidarian.
Sequence alignment of colicin lysis proteins.
Ribbon representations of GAP-oxidizing enzymes in Archaea.
TolA, TolB, and Pal crystal structures.
Models of pilus and pseudopilus fibers.
(A) Crystal structure of the monomer of PGI/PMI from Pyb
Molecular model of the Helicobacter pylori PldA1 dimer.
Structure of an ATP-bound ABC dimer.
Presentation transcript:

Structures of P. aeruginosa ExoU and its chaperone, SpcU (PDB ID 3TU3), shown as a cartoon. Structures of P. aeruginosa ExoU and its chaperone, SpcU (PDB ID 3TU3), shown as a cartoon. SpcU is shown in white, the ExoU chaperone binding domain is in gold, the PLA2 domain is green, and the membrane localization domain is shown in pink and purple. Catalytically important residues are shown as yellow sticks, and the ubiquitylable Lys178 is shown as a space-filling representation. Marietta Flores-Díaz et al. Microbiol. Mol. Biol. Rev. 2016; doi:10.1128/MMBR.00082-15