Rebound kinetics of β2-microglobulin after hemodialysis

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Rebound kinetics of β2-microglobulin after hemodialysis John K. Leypoldt, Alfred K. Cheung, R. Barry Deeter Kidney International Volume 56, Issue 4, Pages 1571-1577 (October 1999) DOI: 10.1046/j.1523-1755.1999.00669.x Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 1 Plasma urea nitrogen concentrations plotted as a function of time after starting the hemodialysis treatment. Symbols are: (▪) low-flux dialyzer; (□) high-flux dialyzer. There was no difference in urea nitrogen concentration between the low-flux and high-flux dialyzers at any time point. The arrow at 210 minutes indicates the end of the hemodialysis treatment (End of HD). Error bars denote ±1 SEM. Kidney International 1999 56, 1571-1577DOI: (10.1046/j.1523-1755.1999.00669.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 2 Fractional changes in plasma volume plotted as a function of time after starting the hemodialysis treatment. Symbols are: (▪) low-flux dialyzer; (□) high-flux dialyzer. There was no difference in changes in plasma volume between the low-flux and high-flux dialyzers at any time point. The arrow at 210 minutes indicates the end of the hemodialysis treatment (End of HD). Error bars denote ±1 SEM. Kidney International 1999 56, 1571-1577DOI: (10.1046/j.1523-1755.1999.00669.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 3 Plasma β2-microglobulin concentrations plotted as a function of time after starting the hemodialysis treatment. Symbols are: (▪) low-flux dialyzer; (□) high-flux dialyzer. Asterisks denote that the plasma β2-microglobulin concentration was higher (*P < 0.01) during treatment with the low-flux than with the high-flux dialyzers. The arrow at 210 minutes indicates the end of the hemodialysis treatment (End of HD). Error bars denote ±1 SEM. Kidney International 1999 56, 1571-1577DOI: (10.1046/j.1523-1755.1999.00669.x) Copyright © 1999 International Society of Nephrology Terms and Conditions

Figure 4 β2-microglobulin clearances calculated using four different methods for both low-flux (▪) and high-flux (□) dialyzers. AV denotes clearance values calculated directly across the dialyzer from arterial and venous concentrations. PP(0), PP(30), and PP(60) denote clearance values calculated from predialysis and postdialysis concentrations using Equations 5 and 6. The number in parentheses denotes the time after ending hemodialysis (in minutes) when the postdialysis concentration was evaluated. Asterisks denote differences (*P < 0.05) in the calculated clearances. Error bars denote ±1 SEM. Kidney International 1999 56, 1571-1577DOI: (10.1046/j.1523-1755.1999.00669.x) Copyright © 1999 International Society of Nephrology Terms and Conditions