Abnormal plasminogen: A genetically determined cause of hypercoagulability Jonathan B. Towne, M.D., Dennis F. Bandyk, M.D., Clara V. Hussey, M.D., Vicki.

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Presentation transcript:

Abnormal plasminogen: A genetically determined cause of hypercoagulability Jonathan B. Towne, M.D., Dennis F. Bandyk, M.D., Clara V. Hussey, M.D., Vicki T. Tollack, B.S. Journal of Vascular Surgery Volume 1, Issue 6, Pages 896-902 (November 1984) DOI: 10.1016/0741-5214(84)90022-3 Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 1 Venogram demonstrating subclavian and axillary vein thrombosis in patient who had separate episodes of arterial and venous thrombosis. Journal of Vascular Surgery 1984 1, 896-902DOI: (10.1016/0741-5214(84)90022-3) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 2 Angiogram of patient in Fig. 1 9 months later demonstrating occlusion of the left common iliac artery. Journal of Vascular Surgery 1984 1, 896-902DOI: (10.1016/0741-5214(84)90022-3) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 3 Angiogram obtained 28 months after film in Fig. 2 showing reocclusion of common iliac artery. Journal of Vascular Surgery 1984 1, 896-902DOI: (10.1016/0741-5214(84)90022-3) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 4 Pedigree of patient's family with abnormal plasminogen. Stippled areas represent family members not tested. Solid areas are members with abnormal plasminogen. Patient's three children all had abnormal plasminogen. Journal of Vascular Surgery 1984 1, 896-902DOI: (10.1016/0741-5214(84)90022-3) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

Fig. 5 Pedigree of patient's family with abnormal plasminogen. Open circle is patient's wife who is only member without abnormal plasminogen. Journal of Vascular Surgery 1984 1, 896-902DOI: (10.1016/0741-5214(84)90022-3) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions