Altered Functional Status of the Hypothalamic Dopaminergic Tone in Patients with Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem.

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Presentation transcript:

Altered Functional Status of the Hypothalamic Dopaminergic Tone in Patients with Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation: A Pilot Study Adalberto Parra, Jorge Ramírez-Peredo, Rocío Hidalgo, Amelia Morales-Toquero, Gabriela Velásquez-Ramírez, Alejandro Ruiz- Argüelles, Guillermo J. Ruiz-Argüelles Biology of Blood and Marrow Transplantation Volume 12, Issue 5, Pages 566-572 (May 2006) DOI: 10.1016/j.bbmt.2005.12.035 Copyright © 2006 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 1 Mean basal serum prolactin concentration and that in response to a 10-mg intravenous bolus of metoclopramide (MCP) in a group of 10 healthy controls, in 5 allografted patients with chronic GVHD, and in 5 allografted patients without GVHD. Values represent the mean ± SEM. Biology of Blood and Marrow Transplantation 2006 12, 566-572DOI: (10.1016/j.bbmt.2005.12.035) Copyright © 2006 American Society for Blood and Marrow Transplantation Terms and Conditions

Figure 2 Individual values for the area under the prolactin curve during the intravenous metoclopramide test in a group of 10 healthy controls, in 5 allografted patients with chronic GVHD, and in 5 allografted patients without GVHD. Biology of Blood and Marrow Transplantation 2006 12, 566-572DOI: (10.1016/j.bbmt.2005.12.035) Copyright © 2006 American Society for Blood and Marrow Transplantation Terms and Conditions