Keith A. Horvath, MD, Kevin T. Schomacker, PhDa, C

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Intraoperative myocardial ischemia detection with laser-induced fluorescence Keith A. Horvath, MD, Kevin T. Schomacker, PhDa, C.Chin Lee, MD, Lawrence H. Cohn, MD The Journal of Thoracic and Cardiovascular Surgery Volume 107, Issue 1, Pages 220-225 (January 1994) DOI: 10.5555/uri:pii:S0022522394704740 Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 1 Laser-induced fluorescence apparatus. The pulsed nitrogen laser is optically coupled to a single 400 μm fiber that transmits the excitation signal to the heart and also returns the fluorescence signal to a polychromator. The fluorescence signal is then recorded with a gated intesified diode array/optical multichannel analyzer. The Journal of Thoracic and Cardiovascular Surgery 1994 107, 220-225DOI: (10.5555/uri:pii:S0022522394704740) Copyright © 1994 Mosby, Inc. Terms and Conditions

Fig. 2 NADH fluorescence in relation to the sequence of events after acute myocardial infarction (occlusion), cardioplegic arrest, cardiopulmonary bypass, and recovery. The black line corresponds to fluorescence in the ischemic area, the dark gray line corresponds to outside the ischemic area, and the light gray line corresponds to the border of the ischemic area. The Journal of Thoracic and Cardiovascular Surgery 1994 107, 220-225DOI: (10.5555/uri:pii:S0022522394704740) Copyright © 1994 Mosby, Inc. Terms and Conditions