Adding lactate to the prime solution during hypothermic cardiopulmonary bypass: a quantitative acid–base analysis D. Himpe, H. Neels, S. De Hert, P.

Slides:

Advertisements

Similar presentations

Halothane potentiates the effect of methamphetamine and nomifensine on extracellular dopamine levels in rat striatum: a microdialysis study Y.U. Adachi,

Advertisements

Impact of xenon anaesthesia in isolated cardiopulmonary bypass on very early leucocyte and platelet activation and clearance: a randomized, controlled.

N.P. Talbot, P.A. Robbins, K.L. Dorrington

C Dualé, C Frey, F Bolandard, A Barrière, P Schoeffler

J Barbara, M.-C. Santais, D.A. Levy, F Ruff, F Leynadier

P. W. Boonstra, MD, PhD, Y. J. Gu, MD, PhD, C. Akkerman, BSc, J

The anion study: effect of different crystalloid solutions on acid base balance, physiology, and survival in a rodent model of acute isovolaemic haemodilution

Estimation of changes in cardiac output from the arterial blood pressure waveform in the upper limb†,†† N.W.F. Linton, R.A.F. Linton British Journal.

Gabapentin prophylaxis for postoperative nausea and vomiting in abdominal surgeries: a quantitative analysis of evidence from randomized controlled clinical.

Effects of an intraoperative infusion of 4% succinylated gelatine (Gelofusine®) and 6% hydroxyethyl starch (Voluven®) on blood volume† S. Awad, S. Dharmavaram,

Differential effects of lidocaine and remifentanil on response to the tracheal tube during emergence from general anaesthesia J.H. Lee, B.-N. Koo, J.-J.

Changes in the effect of propofol in response to altered plasma protein binding during normothermic cardiopulmonary bypass E Takizawa, H Hiraoka, D Takizawa,

Changes in glomerular filtration rate after cardiac surgery with cardiopulmonary bypass in patients with mild preoperative renal dysfunction B.G. Loef,

A different use of visual analytic techniques in anaesthetics

Effects of dexamethasone on clinical course, C-reactive protein, S100B protein and von Willebrand factor antigen after paediatric cardiac surgery L Lindberg,

Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting.

Prediction of volatile anaesthetic solubility in blood and priming fluids for extracorporeal circulation R.-G. Yu, J.-X. Zhou, J Liu British Journal.

Bispectral index, serum drug concentrations and emergence associated with individually adjusted target-controlled infusions of remifentanil and propofol.

Perioperative hyperinsulinaemic normoglycaemic clamp causes hypolipidaemia after coronary artery surgery† C.J. Zuurbier, F.J. Hoek, J. van Dijk, N.G.

Recent advances in gas exchange measurement in intensive care patients

Comparison of remifentanil and alfentanil during anaesthesia for patients undergoing direct laryngoscopy without intubation E. Wiel, M. Davette, L. Carpentier,

M.A. Olympio, R. Whelan, R.P.A. Ford, I.C.M. Saunders

Modification of tracheal tubes

Pain after orthopaedic surgery: differences in patient reported outcomes in the United States vs internationally. An observational study from the PAIN.

Effects of cardiopulmonary bypass on neurocognitive performance and cytokine release in old and diabetic rats F. de Lange, J.M. Dieleman, B. Jungwirth,

Neuromuscular junction in health and disease

Preoperative levosimendan infusion in combined aortic valve and coronary bypass surgery H Leppikangas, K Järvelä, T Sisto, P Maaranen, M Virtanen, P.

Detection of awareness in surgical patients with EEG-based indices—bispectral index and patient state index†‡ G. Schneider, A.W. Gelb, B. Schmeller,

Effect of continuous low-dose intravenous diltiazem on epidural fentanyl analgesia after lower abdominal surgery K. Nitahara, M. Matsunaga, K. Katori,

D.H.J. Davis, M. Oliver, A.J. Byrne British Journal of Anaesthesia

Could ultrasonography be used by an anaesthetist to identify a specified lumbar interspace before spinal anaesthesia? M.J. Watson, S. Evans, J.M. Thorp

Profound haemodilution during normothermic cardiopulmonary bypass influences neither gastrointestinal permeability nor cytokine release in coronary artery.

Xenon has no effect on cytokine balance and adhesion molecule expression within an isolated cardiopulmonary bypass system†‡ A. Bedi, W.T. McBride, M.A.

R.N. Upton, G.L. Ludbrook, A.M. Martinez, C Grant, R.W. Milne

Block of the sacral segments in lumbar epidural anaesthesia

Do team processes really have an effect on clinical performance

Digital ischaemia after ulnar artery cannulation

B. McNamara, J. Ray, D. Menon, S. Boniface

D. Jee, D. Lee, S. Yun, C. Lee British Journal of Anaesthesia

Expertise in practice: an ethnographic study exploring acquisition and use of knowledge in anaesthesia A. Smith, D. Goodwin, M. Mort, C. Pope British.

Cerebral hyperthermia during cardiopulmonary bypass in adults

Age- and therapy-related effects on morphine requirements and plasma concentrations of morphine and its metabolites in postoperative infants N.J. Bouwmeester,

Diastolic dysfunction, cardiopulmonary bypass, and atrial fibrillation after coronary artery bypass graft surgery C.M. Ashes, M. Yu, M. Meineri, R. Katznelson,

Changes in serum albumin concentration and volume expanding effects following a bolus of albumin 20% in septic patients Margarson M.P. , Soni N.C.

S Singh, J.E. Smith British Journal of Anaesthesia

Dexamethasone decreases the pro- to anti-inflammatory cytokine ratio during cardiac surgery S.R. El Azab, P.M.J. Rosseel, J.J. de Lange, A.B.J. Groeneveld,

The output of two sevoflurane vaporizers in the presence of helium

Anaesthesia for awake craniotomy—evolution of a technique that facilitates awake neurological testing A. Sarang, J. Dinsmore British Journal of Anaesthesia

Comparison of 1% and 2% lidocaine epidural anaesthesia combined with sevoflurane general anaesthesia utilizing a constant bispectral index A Shono, S.

Real-time breath monitoring of propofol and its volatile metabolites during surgery using a novel mass spectrometric technique: a feasibility study G.R.

J.E. Heavner, A.D. Kaye, B.-K. Lin, T. King

U. Eichenberger, C. Giani, S. Petersen-Felix, T. Graven-Nielsen, L

Prothrombin complex concentrate mitigates diffuse bleeding after cardiopulmonary bypass in a porcine model F Kaspereit, S Hoffmann, I Pragst, G Dickneite

Heritable differences in respiratory drive and breathing pattern in mice during anaesthesia and emergence† H. Groeben, S. Meier, C.G. Tankersley, W.

N. A. Guzzetta, F. Szlam, A. S. Kiser, J. D. Fernandez, A. D. Szlam, T

Recovery of fibrinogen after administration of fibrinogen concentrate to patients with severe bleeding after cardiopulmonary bypass surgery C. Solomon,

Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery F Weis, A Beiras-Fernandez, D Hauer,

J.-L. Vincent, M.M. Wilkes, R.J. Navickis

Comparison of ropivacaine 0. 5% (in glucose 5%) with bupivacaine 0

Cross-tolerance between spinal neostigmine and morphine in the rat

Fractal or biologically variable delivery of cardioplegic solution prevents diastolic dysfunction after cardiopulmonary bypass M.R. Graham, MDa, R.K.

Haemodynamic effects of oxytocin given as i. v

B.H. Cuthbertson, S.A. Stott, N.R. Webster

Another case of obstruction to an anaesthetic circuit

Levosimendan pre-treatment improves outcomes in patients undergoing coronary artery bypass graft surgery† L. Tritapepe, V. De Santis, D. Vitale, F. Guarracino,

Effect of concentration of local anaesthetic solution on the ED50 of bupivacaine for supraclavicular brachial plexus block† P.K. Gupta, P.M. Hopkins

Monitoring level of sedation with bispectral EEG analysis: comparison between hypothermic and normothermic cardiopulmonary bypass† D. Schmidlin, P. Hager,

Y.John Gu, MD, PhD, Piet W. Boonstra, MD, PhD, Willem van Oeveren, PhD

Effect of isotonic versus hypotonic maintenance fluid therapy on urine output, fluid balance, and electrolyte homeostasis: a crossover study in fasting.

Effects of dexmedetomidine on adrenocortical function, and the cardiovascular, endocrine and inflammatory responses in post-operative patients needing.

Presentation transcript:

Adding lactate to the prime solution during hypothermic cardiopulmonary bypass: a quantitative acid–base analysis D. Himpe, H. Neels, S. De Hert, P. Van Cauwelaert British Journal of Anaesthesia Volume 90, Issue 4, Pages 440-445 (April 2003) DOI: 10.1093/bja/aeg084 Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 1 Changes in (a) haemoglobin concentration (b) and colloid osmotic pressure expressed as mean±2 sem before (T1), during (T2) and at the end (T3) of CPB. A significant but similar haemodilution occurred in both groups (P<0.05, T2 and T3 compared with T1, not shown). Colloid osmotic pressure was well maintained over time, with no difference between groups. British Journal of Anaesthesia 2003 90, 440-445DOI: (10.1093/bja/aeg084) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 2 Changes in lactate levels over time expressed as mean ±2 sem. At the start of hypothermic CPB (Ts), lactate was significantly more elevated in Group I (*P<0.05). Lactate levels also increased in Group II. After 40 min (T2) and at the end of CPB (T3), lactate levels in the two groups were in the same range and remained significantly elevated compared with baseline values (T1) (‡P<0.05). British Journal of Anaesthesia 2003 90, 440-445DOI: (10.1093/bja/aeg084) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions

Fig 3 Gamble diagrams illustrating the composition in mEq litre–1of positive and negative charges of serum ions before (T1) and by the end of bypass (T3). The total mEqs are slightly greater in both groups at T3, corresponding to the larger observed osmotic pressures. Significant within-group differences (‡P<0.05) over time in ionic composition are noted for both groups at T1 compared with T3. Significant differences in the global ionic composition between groups at T3 are also shown (*P<0.05). Details on individual ion levels are shown in Table 2. British Journal of Anaesthesia 2003 90, 440-445DOI: (10.1093/bja/aeg084) Copyright © 2003 British Journal of Anaesthesia Terms and Conditions